RT Journal A1 Mofenson LM T1 SUccesses and challenges in the perinatal hiv-1 epidemic in the united states as illustrated by the hiv-1 serosurvey of childbearing women JF Archives of Pediatrics & Adolescent Medicine JO Archives of Pediatrics & Adolescent Medicine YR 2004 FD May 1 VO 158 IS 5 SP 422 OP 425 DO 10.1001/archpedi.158.5.422 UL http://dx.doi.org/10.1001/archpedi.158.5.422 AB Almost all human immunodeficiency virus type 1 (HIV-1) infections in children in the United States, as well as globally, are secondary to mother-to-child transmission (MTCT) of the virus. In the past decade, there has been impressive success in the United States and other resource-rich countries in reducing incident pediatric HIV-1 infections and a concomitant dramatic decrease in the incidence of new cases of pediatric AIDS.1 In contrast, in resource-limited settings, initiation of testing programs to allow pregnant women to learn their HIV-1 serostatus and use of effective short-course antiretroviral interventions to prevent MTCT are just now beginning to be implemented.2