RT Journal A1 Mahant S, Cohen E, Weinstein M, Wadhwa A T1 Video-assisted thorascopic surgery vs chest drain with fibrinolytics for the treatment of pleural empyema in children: A systematic review of randomized controlled trials JF Archives of Pediatrics & Adolescent Medicine JO Archives of Pediatrics & Adolescent Medicine YR 2010 FD February 1 VO 164 IS 2 SP 201 OP 203 DO 10.1001/archpediatrics.2009.271 UL http://dx.doi.org/10.1001/archpediatrics.2009.271 AB There is marked variability in treatment of pleural empyema in children1- 2 and a debate over whether video-assisted thoracoscopic surgery (VATS) is more effective than chest drain with fibrinolytics. A meta-analysis of observational studies and subsequent large observational studies concluded that surgical management, in particular VATS, is most effective.1- 3 We conducted a systematic review of randomized controlled trials (RCTs) to compare the effectiveness of these treatments for pleural empyema in children.