RT Journal
A1 Ali A
T1 HElicobacter pylori and infantile colic
JF Archives of Pediatrics & Adolescent Medicine
JO Archives of Pediatrics & Adolescent Medicine
YR 2012
FD July 1
VO 166
IS 7
SP 648
OP 650
DO 10.1001/archpediatrics.2011.1241
UL http://dx.doi.org/10.1001/archpediatrics.2011.1241
AB Objective 
                  To determine whether Helicobacter pylori is associated with infantile colic.Design 
                  Case-control study.Settings 
                  Local tertiary hospital in rural Gizan, Saudi Arabia.Participants 
                  A total of 55 patients with infantile colic who were 2 weeks to 4 months of age and who fulfilled modified Wessel criteria (ie, crying and fussy behavior) and a total of 30 healthy controls with no history of colic who were matched by country of origin, age, sex, and ethnicity to the 55 colicky infants.Main Outcome Measure 
                  Helicobacter pylori infection determined by H pylori stool antigen testing.Results 
                  Of the 55 patients presenting with infantile colic, 45 (81.8%) tested positive for H pylori ; of the 30 healthy controls, 7 (23.3%) tested positive for H pylori (odds ratio, 15.3 [95% CI, 17.9-29.8]).Conclusion 
                  H pylori infection is associated with infantile colic and may be a causative factor.