RT Journal A1 Chau V, Poskitt K, Miller S T1 Magnetic resonance imaging in hypoxic-ischemic encephalopathy: Still a cool test JF Archives of Pediatrics & Adolescent Medicine JO Archives of Pediatrics & Adolescent Medicine YR 2012 FD July 1 VO 166 IS 7 SP 669 OP 671 DO 10.1001/archpediatrics.2012.579 UL http://dx.doi.org/10.1001/archpediatrics.2012.579 AB Hypoxic-ischemic brain injury, the most frequent cause of neonatal encephalopathy, carries high rates of morbidity and mortality, accounting for up to 20% of deaths in the neonatal population.1 In surviving children, 15% to 20% will sustain permanent neurodevelopmental disability, including impaired motor skills and cognition.2 In diagnosing this condition, early clinical indicators such as umbilical cord pH and Apgar scores do not reliably predict long-term outcomes.3 The severity of clinical encephalopathy seems to be a stronger predictor of neurodevelopment,4 but its predictive value is limited in the subgroup of newborns presenting with moderate symptoms.5- 7