RT Journal T1 Clinical studies of besnier's prurigo (synonyms: Atopic dermatitis, eczema pruriginosum allergicum, neurodermatitis disseminata) with special reference to its course, the significance of airborne allergens and the value of certain methods of treatment. JF American Journal of Diseases of Children JO American Journal of Diseases of Children YR 1949 FD July 1 VO 78 IS 1 SP 140 OP 140 DO 10.1001/archpedi.1949.02030050149015 UL http://dx.doi.org/10.1001/archpedi.1949.02030050149015 AB This work constitutes an exhaustive report of clinical investigation done by the author in Denmark on Besnier's prurigo (atopic dermatitis) during more than two years and involving case studies on 100 patients.After an excellent characterization of the disease and its course, the author passes to a consideration of various factors which appear to influence the course, with special reference to allergy to inhalants which, in his opinion, is one of the most important factors. Cutaneous testing and its significance are well considered. The final sections deal with therapy, and he expresses his feeling that symptomatic local treatment and change of environment are the most effective forms. Generalized use of ultraviolet rays is looked on with favor in treatment of older children, adolescents and adults. Specific desensitization is regarded by the author as being "not generally recommendable for Besnier's prurigo."From a casuistic point of view this is a most