RT Journal
T1 POlycories (storage diseases).
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1949
FD May 1
VO 77
IS 5
SP 688
OP 688
DO 10.1001/archpedi.1949.02030040702014
UL http://dx.doi.org/10.1001/archpedi.1949.02030040702014
AB This monograph represents a thorough discussion of the storage diseases, a rare but interesting group of metabolic disturbances. The author, who has done considerable original work in this field judging from his extensive list of publications, proposes the term "polycories," of Greek origin and meaning "much saturation," and defines the diseases as characterized by the excessive accumulation of substances that occur normally in the organ-specific cells, due to a constitutional neurohormonal disturbance. In the clinical description, the author uses as a source his own observations, showing for example, photographs of a child observed from the sixth to the twentieth year of life, as well as reports from the literature. He describes the laboratory findings in detail and uses graphs to explain the chemical behavior of the metabolic functions of the organs involved.Discussed are the glycogen and fat storage diseases of the liver, with brief mention of the involvement of