RT Journal A1 SPAHR MB T1 THe bacteriology of mastoiditis in infants JF American Journal of Diseases of Children JO American Journal of Diseases of Children YR 1929 FD March 1 VO 37 IS 3 SP 541 OP 545 DO 10.1001/archpedi.1929.01930030083007 UL http://dx.doi.org/10.1001/archpedi.1929.01930030083007 AB Ever since Hartmann,1 in 1898, followed by Preysing2 in 1904, noted in infants digestive disturbance associated with disease of the middle ear, the rĂ´le of parenteral infection in gastro-intestinal disturbance has been under consideration.In 1921, Maurice Renaud,3 in seventy autopsies in cases of diarrhea, found suppuration of the middle ear and mastoid in every case, but did not discover any pathologic condition of the gastro-intestinal tract. Floyd,4 in 1925, reported twenty-six cases, occurring within eighteen months, with symptoms of gastro-intestinal disturbance, toxicity and loss of weight, in infants from 8 to 15 months of age. The earlier cases did not show any response to medical treatment, and autopsy revealed only pus, too thick to flow, in the mastoids. Mastoidectomy in such cases gave good results.At the St. Louis Children's Hospital, similar cases have been studied in an effort to correlate the clinical observations with