RT Journal
A1 Cusick SE, Georgieff MK
T1 Nutrient supplementation and neurodevelopment: Timing is the key
JF Archives of Pediatrics & Adolescent Medicine
JO Archives of Pediatrics & Adolescent Medicine
YR 2012
FD May 1
VO 166
IS 5
SP 481
OP 482
DO 10.1001/archpediatrics.2012.199
UL http://dx.doi.org/10.1001/archpediatrics.2012.199
AB 
The human brain develops throughout a person's life span and is dependent on an adequate supply of nutrients to support its development.1 One of the most rapid periods of overall brain growth occurs during the last trimester in the fetus through the first 3 postnatal years.2 Thus, there is a major public health emphasis on promoting nutritional adequacy during these formative years in order to optimize developmental outcome. The brain, however, is not a homogenous organ with respect to its development. Individual brain regions (eg, the hippocampus and the prefrontal cortex) and processes (eg, myelination) exhibit variable trajectories with respect to the timing of the onset of development and the speed of development.2