RT Journal A1 Rivara FP T1 SEarching for effective treatment JF Archives of Pediatrics & Adolescent Medicine JO Archives of Pediatrics & Adolescent Medicine YR 2011 FD December 1 VO 165 IS 12 SP 1137 OP 1138 DO 10.1001/archpediatrics.2011.194 UL http://dx.doi.org/10.1001/archpediatrics.2011.194 AB In this issue of Archives, there is yet another article on the treatment of acute bronchiolitis, this time using helium-oxygen mixtures.2 It is a good article, with strong methods and positive results, and we are proud to publish it. However, the Archives of Pediatrics & Adolescent Medicine has published many such articles on the treatment of bronchiolitis and respiratory syncytial virus infections (eg, use of inhaled nitric oxide,3 3% hypertonic saline with epinephrine,4 and epinephrine vs albuterol5) and reviews on the diagnosis6 and treatment7 of this disorder. Usually when there are so many different treatments suggested for a disorder, none is entirely efficacious, which accounts for the frequent hospitalizations and sometimes long lengths of hospital stay for children with these infections. This is certainly the case for respiratory syncytial virus infections and bronchiolitis.