RT Journal A1 Torchia D, Schachner LA T1 PIcture of the month—quiz case JF Archives of Pediatrics & Adolescent Medicine JO Archives of Pediatrics & Adolescent Medicine YR 2011 FD August 1 VO 165 IS 8 SP 763 OP 763 DO 10.1001/archpediatrics.2011.120-a UL http://dx.doi.org/10.1001/archpediatrics.2011.120-a AB When seen at age 5 years, he still had widespread chronic eczema. In addition, erythematous and infiltrative lesions surmounted by scales and crusts were evident in a circinate pattern (Figure). Scalp and eyebrow hair did not show any abnormality clinically or on dermatoscopic and microscopic examination. Multiple skin cultures isolated methicillin-resistant Staphylococcus aureus. Serum IgE and blood eosinophil levels were elevated; dosage of specific IgE showed positivity toward several airborne and food allergens. Topical emollients, corticosteroids (hydrocortisone butyrate, triamcinolone), calcineurin inhibitors (tacrolimus, pimecrolimus), bleach baths, and nasal mupirocin achieved only mild improvement of cutaneous lesions. The diagnosis was achieved by genetic testing.