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Editorial  | 
Reconsideration of Age as a Contraindication for Curative Therapy of Sickle Cell Disease
Allison A. King, MD, MPH; John F. DiPersio, MD, PhD
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JAMA Guide to Statistics and Methods  | 
The Intention-to-Treat Principle:  How to Assess the True Effect of Choosing a Medical Treatment
Michelle A. Detry, PhD; Roger J. Lewis, MD, PhD
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Original Investigation  | 
Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury:  A Randomized Clinical Trial
Claudia S. Robertson, MD; H. Julia Hannay, PhD; José-Miguel Yamal, PhD; et al.