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Necrotizing Enterocolitis: Title and subTitle BreakEpidemic Following an Outbreak of Enterobacter cloacae Type 3305573 in a Neonatal Intensive Care Unit FREE

Julie Powell, MD; Michel A. Bureau, MD, FRCP(C); Claude Paré, MD; Marie-Lyse Gaildry, MD; Diane Cabana, MD; Heidi Patriquin, MD, FRCP(C)
[+] Author Affiliations

Reprint requests to Département de Pédiatrie, Faculté de Médecine, Sherbrooke, Québec, Canada J1H 5N4 (Dr Bureau).


Arch Pediatr Adolesc Med. 1980;134(12):1152-1154. doi:10.1001/archpedi.1980.02130240036011
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• Twelve cases of necrotizing enterocolitis (NEC) occurred within three weeks in a neonatal intensive care unit (NICU) with 325 annual admissions. Enterobacter cloacae type 3305573 was found in stool and/or blood cultures from affected babies prior to the onset of the disease. This bacterium could not be grown in cultures from infants in the same NICU six weeks later. A causal relationship between E cloacae and the epidemic of NEC is suggested.

(Am J Dis Child 134:1152-1154, 1980)

REFERENCES

Virnig NL, Reynolds JW:  Epidemiological aspects of neonatal necrotizing enterocolitis . Am J Dis Child 128:186-190, 1974;.
Speer ME, Taber LH, Yow MD, et al:  Fulminant neonatal sepsis and necrotizing associated with a 'nonenteropathogenic' strain of Escherichia coli . J Pediatr 89:91-95, 1976;.
Hill HR, Hunt CE, Matsen JM:  Nosocomial colonization with Klebsiella type 26 in neonatal ICU associated with an outbreak of sepsis, meningitis, and NEC . J Pediatr 85:415-419, 1974;.
Stein H, Beck J, Solomon A, et al:  Gastroenteritis with necrotizing enterocolitis in premature babies . Br Med J 2:616-619, 1972;.
Howard FM, Flynn DM, Bradley JM, et al:  Outbreak of necrotizing enterocolitis caused by Clostridium butyricum . Lancet 2:1099-1102, 1977;.
Guinan M, Schaberg D, Bruhn FW, et al:  Epidemic occurrence of neonatal necrotizing enterocolitis . Am J Dis Child 133:594-597, 1979;.
Book LS, Overall JC, Herbst JJ, et al:  Clustering of necrotizing enterocolitis: Interruption by infection-control measures . N Engl J Med 297:984-986, 1977;.
Bell MJ, Ternberg JL, Feigin RD, et al:  Neonatal necrotizing enterocolitis: Therapeutic decision based upon clinical staging . Ann Surg 187:1-7, 1978;.
Stoll BJ, Kanto WP, Glass RI, et al:  Epidemiology of necrotizing enterocolitis: A case control study . J Pediatr 96:447-451, 1980;.

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Virnig NL, Reynolds JW:  Epidemiological aspects of neonatal necrotizing enterocolitis . Am J Dis Child 128:186-190, 1974;.
Speer ME, Taber LH, Yow MD, et al:  Fulminant neonatal sepsis and necrotizing associated with a 'nonenteropathogenic' strain of Escherichia coli . J Pediatr 89:91-95, 1976;.
Hill HR, Hunt CE, Matsen JM:  Nosocomial colonization with Klebsiella type 26 in neonatal ICU associated with an outbreak of sepsis, meningitis, and NEC . J Pediatr 85:415-419, 1974;.
Stein H, Beck J, Solomon A, et al:  Gastroenteritis with necrotizing enterocolitis in premature babies . Br Med J 2:616-619, 1972;.
Howard FM, Flynn DM, Bradley JM, et al:  Outbreak of necrotizing enterocolitis caused by Clostridium butyricum . Lancet 2:1099-1102, 1977;.
Guinan M, Schaberg D, Bruhn FW, et al:  Epidemic occurrence of neonatal necrotizing enterocolitis . Am J Dis Child 133:594-597, 1979;.
Book LS, Overall JC, Herbst JJ, et al:  Clustering of necrotizing enterocolitis: Interruption by infection-control measures . N Engl J Med 297:984-986, 1977;.
Bell MJ, Ternberg JL, Feigin RD, et al:  Neonatal necrotizing enterocolitis: Therapeutic decision based upon clinical staging . Ann Surg 187:1-7, 1978;.
Stoll BJ, Kanto WP, Glass RI, et al:  Epidemiology of necrotizing enterocolitis: A case control study . J Pediatr 96:447-451, 1980;.

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