Radiological Case of the Month FREE

Allen E. Eskenazi, MD; Andrew B. Campbell, MD

Arch Pediatr Adolesc Med. 1997;151(10):1051-1052. doi:10.1001/archpedi.1997.02170470085016.

Text Size: A A A

Published online

Article

References

Comments

ABSTRACT

ABSTRACT | REFERENCES

A 4-YEAR-OLD child was diagnosed with a stage III embryonal rhabdomyosarcoma arising in the left maxillary sinus without distant metastatic disease. He was treated with vincristine sulfate, ifosfamide, etoposide, dactinomycin, cyclophosphamide, and local radiotherapy. Two weeks after the completion of all chemotherapy, a routine computed tomographic scan of the chest was performed as part of his end-of-therapy restaging (Figure 1). That evening, several cutaneous vesicular lesions and a low-grade fever developed. He was seen by his physician 5 days later, at which time he had diffuse skin and intraoral eruptions of umbilicated vesicular lesions. Pulmonary examination results were remarkable for a respiratory rate of 25/min and diffuse respiratory crackles and expiratory wheezes. He was treated with a 7-day course of intravenous acyclovir (1500 mg/m² per day), and oxygen via a nasal cannula, and nebulized albuterol for intermittent hypoxia and wheezing. Throughout his course of chemotherapy for cancer and for

REFERENCES

ABSTRACT | REFERENCES

Davis SD. CT evaluation for pulmonary metastases in patients with extrathoracic malignancy . Radiology . 1991;;180:1-12.

Cohen M, Grosfeld J, Baehner R, Weetman R. Lung CT for detection of metastases: solid tissue neoplasms in children . AJR Am J Roentgenol . 1982;;139:895-898.

Cohen M, Smith WL, Weetman R, Provisor A. Pulmonary pseudometastases in children with malignant tumors . Radiology . 1981;;141:371-374.

Fleisher G, Henry W, McSorley M, Arbeter A, Plotkin S. Life-threatening complications of varicella . AJDC . 1981;;135:896-899.

Preblud SR. Varicella: complications and costs . Pediatrics . 1986;;78( (suppl) ):728-735.

Feldman S, Lott L. Varicella in children with cancer: impact of antiviral therapy and prophylaxis . Pediatrics . 1987;;80:465-472.

Mayo DR, Booss J. Varicella zoster–associated neurologic disease without skin lesions . Arch Neurol . 1989;;46:313-315.

Asano Y, Itakura N, Hiroishi Y, et al. Viremia is present in incubation period in nonimmunocompromised children with varicella . J Pediatr . 1985;;106:69-71.

Rowland P, Wald ER, Mirro JR Jr, et al. Progressive varicella presenting with pain and minimal skin involvement in children with acute lymphoblastic leukemia . J Clin Oncol . 1995;;13:1697-1703.

Gogos CA, Bassaris HP, Vagenakis AG. Varicella pneumonia in adults: a review of pulmonary manifestations, risk factors, and treatment . Respiration . 1992;;59: 339-343.

Meyer B, Stalder H, Wegmann W. Persistent pulmonary granulomas after recovery from varicella pneumonia . Chest . 1986;;89:457-459.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal