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Pathological Case of the Month FREE

Shohreh Iravani, MD; Arthur Walling, MD; Enid Gilbert-Barness, MD
Arch Pediatr Adolesc Med. 1997;151(4):427-428. doi:10.1001/archpedi.1997.02170410101016.
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A 17-YEAR-OLD boy was seen with a slowly enlarging, painful mass over the anterior aspect of his left tibia. The lesion was first noticed approximately 3 to 4 years ago, at which time it was small.

Results of a physical examination revealed a mass, 4 × 3 cm, overlying the distal aspect of the diaphysealmetaphyseal junction. There was no history of trauma to this site. The patient had full range of motion of his ankle and knee. He had no neurovascular abnormalitites and no palpable lymphadenopathy. The white blood cell count and sedimentation rate results were within normal limits. Further diagnostic evaluation, including radiographic studies (Figure 1), computed tomographic scan (Figure 2), and incisional biopsy (Figure 3 and Figure 4), was performed.

Diagnosis and Discussion

Adamantinoma

A damantinoma is a rare, slow-growing, low-grade malignant tumor that accounts for approximately 0.1% to 0.5 % of all malignant bone tumors.1,2 Its behavior

REFERENCES

Huvos AG, ed.  Adamantinoma of extragnathic bones . In: Bone Tumors: Diagnosis, Treatment, and Prognosis . 2nd ed. Philadelphia, Pa: WB Saunders Co; 1991;:677-693.
Hazelbag HM, Taminiau AH, Fleuren GJ, Hogendoorn PC.  Adamantinoma of the long bones . J Bone Joint Surg Am . 1994;;76:1482-1499.
Gianoutsos MP, Marsden FW, McCarthy SW, Lee KK.  Ulnar adamantinoma . J Hand Surg [Am] . 1994;;19A:495-499.
Conway WF, Hayes CW.  Adamantinoma . Radiol Clin North Am . 1993;;31:354-358.
Rosal J.  Adamantinoma of long bones . In: Rosai J, ed. Ackerman's Surgical Pathology . 7th ed. New York, NY: Raven Press; 1989;;2:1509.
Bloem JL, van der Heul RO, Schuttevaer HM, Kuipers D.  Fibrous dysplasia vs adamantinoma of the tibia . Am J Radiol (AJR) . 1991;;156:1017-1023.
Spjut HJ, Ayala AG.  Skeletal tumors in childhood and adolescence . In: Bennington JL, ed. Pathology of Neoplasia in Children and Adolescents . Philadelphia, Pa: WB Saunders Co. 1986;:256-272.
Young JWR, Aisner SC, Resnik CS, Levine AM, Dorfman HD, Whitley NO.  Case report 660: adamantinoma of the tibia . Skeletal Radiol . 1991;;20:152-156.
Springfield DS, Rosenberg AE, Mankin HJ, Mindell ER.  Relationship between osteofibrous dysplasia and adamantinoma . Clin Orthop . 1994;;309:234-244.
Ishida T, lijima T, Kikuchi F, et al.  A clinicopathological and immunohistochemical study of osteofibrous dysplasia, differentiated adamantinoma, and adamantinoma of long bones . Skeletal Radiol . 1992;;21:493-502.
VanderWilde RS, Pritchard DJ.  Adamantinoma of the tibia . Orthopedics . 1992;; 15:950-953.
Sweet DE, Vinh TN, Devaney K.  Cortical osteofibrous dysplasia of long bone and its relationship to adamantinoma . Am J Surg Pathol . 1992;;16:282-290.
Ueda Y, Blasius S, Edel G, Wuisman P, Bocker W, Roessner A.  Osteofibrous dysplasia of long bones . J Cancer Res Clin Oncol . 1992;;118:152-156.
Lokich J.  Metastatic adamantinoma of bone to lung . Am J Clin Oncol 1994;; 17:157-159.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Huvos AG, ed.  Adamantinoma of extragnathic bones . In: Bone Tumors: Diagnosis, Treatment, and Prognosis . 2nd ed. Philadelphia, Pa: WB Saunders Co; 1991;:677-693.
Hazelbag HM, Taminiau AH, Fleuren GJ, Hogendoorn PC.  Adamantinoma of the long bones . J Bone Joint Surg Am . 1994;;76:1482-1499.
Gianoutsos MP, Marsden FW, McCarthy SW, Lee KK.  Ulnar adamantinoma . J Hand Surg [Am] . 1994;;19A:495-499.
Conway WF, Hayes CW.  Adamantinoma . Radiol Clin North Am . 1993;;31:354-358.
Rosal J.  Adamantinoma of long bones . In: Rosai J, ed. Ackerman's Surgical Pathology . 7th ed. New York, NY: Raven Press; 1989;;2:1509.
Bloem JL, van der Heul RO, Schuttevaer HM, Kuipers D.  Fibrous dysplasia vs adamantinoma of the tibia . Am J Radiol (AJR) . 1991;;156:1017-1023.
Spjut HJ, Ayala AG.  Skeletal tumors in childhood and adolescence . In: Bennington JL, ed. Pathology of Neoplasia in Children and Adolescents . Philadelphia, Pa: WB Saunders Co. 1986;:256-272.
Young JWR, Aisner SC, Resnik CS, Levine AM, Dorfman HD, Whitley NO.  Case report 660: adamantinoma of the tibia . Skeletal Radiol . 1991;;20:152-156.
Springfield DS, Rosenberg AE, Mankin HJ, Mindell ER.  Relationship between osteofibrous dysplasia and adamantinoma . Clin Orthop . 1994;;309:234-244.
Ishida T, lijima T, Kikuchi F, et al.  A clinicopathological and immunohistochemical study of osteofibrous dysplasia, differentiated adamantinoma, and adamantinoma of long bones . Skeletal Radiol . 1992;;21:493-502.
VanderWilde RS, Pritchard DJ.  Adamantinoma of the tibia . Orthopedics . 1992;; 15:950-953.
Sweet DE, Vinh TN, Devaney K.  Cortical osteofibrous dysplasia of long bone and its relationship to adamantinoma . Am J Surg Pathol . 1992;;16:282-290.
Ueda Y, Blasius S, Edel G, Wuisman P, Bocker W, Roessner A.  Osteofibrous dysplasia of long bones . J Cancer Res Clin Oncol . 1992;;118:152-156.
Lokich J.  Metastatic adamantinoma of bone to lung . Am J Clin Oncol 1994;; 17:157-159.

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