0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Reputed Brain Damage and 'Serious' Reactions From DTP Vaccines

Samuel Sepkowitz, MD
Arch Pediatr Adolesc Med. 1997;151(1):107-108. doi:10.1001/archpedi.1997.02170380111026.
Text Size: A A A
Published online

Children have reactions to the diphtheria and tetanus toxoids and pertussis vaccine (DTP), but whether they have serious reactions is a matter of dispute, definition, and, perhaps, intention. The articles by Rosenthal et al1,2 concerning the safety of whole-cell vaccine and the newly licensed acellular vaccine mentioned the word "serious" many times: reactions were characterized as serious, serious adverse, and, as a variation, severe events. Because more serious neurologic events were not reported in the prelicensure trials of the new acellular vaccines, Rosenthal et al have pursued reputed serious reactions from a much larger database, that of the United States, the largest denominator in the industrialized world.

It has been, and still is, the position of the Centers for Disease Control and Prevention, Atlanta, Ga, and the National Childhood Vaccine Injury Act that acute encephalopathy can rarely follow DTP vaccination. Yet, in this study of the United States from

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();