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Pathological Case of the Month FREE

Sonya R. Arnold, MD; Orestes Borrego, MD; Enid Gilbert-Barness, MD
Arch Pediatr Adolesc Med. 1996;150(11):1217-1218. doi:10.1001/archpedi.1996.02170360107020.
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A MALE INFANT, weighing 2845 g, was born at 42 weeks' gestation to a 27-year-old, gravida 1, para 0 mother. The pregnancy was complicated by a group B streptococcal infection in the mother. Labor was induced and complicated by fetal distress. The infant was delivered by cesarean section amid thick meconium fluid. A chest x-ray film showed moderate lung disease and small bilateral infiltrates (Figure 1). The infant had multiple neurological symptoms, including a staring gaze, dilated pupils that were unresponsive to light, and lip smacking. There was no response to tactile stimuli, and deep tendon reflexes were absent in all extremities. The infant's condition continued to deteriorate, with a failed response to high-frequency ventilation. Arterial blood gas values were as follows: pH, 6.82; oxygen pressure, 12 mm Hg; carbon dioxide pressure, 98 mm Hg; oxygen saturation, 5%; base excess, −20 mEq/L; and bicarbonate, 10 mEq/L. Extracorporeal membrane oxygenation therapy

REFERENCES

Katz VL, Bowes WA.  Meconium aspiration syndrome: reflections on a murky subject . Am J Obstet Gynecol . 1992;;166:171-183.
Wiswell TE, Bent RC.  Meconium aspiration and the meconium aspiration syndrome: unresolved issues . Pediatr Clin North Am . 1993;;40:955-981.
Gautham KS, Narang A.  Reply to meconium aspiration syndrome: recent concepts . Ind Pediatr . 1994;;31:1001-1002.
Kumar A, Mishra PK.  Meconium aspiration syndrome: recent concepts . Ind Pediatr . 1993;;30:5-7.
Moore CS.  Meconium aspiration syndrome . Neonat Network . 1994;;13:57-60.
Behrman RE, ed. Nelson Textbook of Pediatrics . 14th ed. Philadelphia, Pa: WB Saunders Co;1992;:469-470.
Cunningham FG, MacDonald PC, Leveno KJ, Gant NF, Gilstrap LC III, eds. Williams Obstetrics . 19th ed. Baltimore, Md: Williams & Wilkins;1993;:995-996.
Gregory GA, Gooding CA, Phibbs RH. Tooley WH.  Meconium aspiration in infants: a prospective study . J Pediatr . 1974;;85:848-852.
Murphy JD, Vawter GF, Reid LM.  Pulmonary vascular disease in fatal meconium aspiration . J Pediatr . 1984;;104:758-762.
Cunningham AS, Lawson EE, Martin RJ, Pildes RS.  Tracheal suction and meconium: a proposed standard of care . J Pediatr . 1990;;116:153-154.
Stocker JT, Dehner LP. Pediatric Pathology . Philadelphia, Pa: JB Lippincott Co; 1992;:545.
Yuksel B, Greenough A, Gamsu HR.  Neonatal meconium aspiration syndrome and respiratory morbidity during infancy . Pediatr Pulmonol . 1993;;16:358-361.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Katz VL, Bowes WA.  Meconium aspiration syndrome: reflections on a murky subject . Am J Obstet Gynecol . 1992;;166:171-183.
Wiswell TE, Bent RC.  Meconium aspiration and the meconium aspiration syndrome: unresolved issues . Pediatr Clin North Am . 1993;;40:955-981.
Gautham KS, Narang A.  Reply to meconium aspiration syndrome: recent concepts . Ind Pediatr . 1994;;31:1001-1002.
Kumar A, Mishra PK.  Meconium aspiration syndrome: recent concepts . Ind Pediatr . 1993;;30:5-7.
Moore CS.  Meconium aspiration syndrome . Neonat Network . 1994;;13:57-60.
Behrman RE, ed. Nelson Textbook of Pediatrics . 14th ed. Philadelphia, Pa: WB Saunders Co;1992;:469-470.
Cunningham FG, MacDonald PC, Leveno KJ, Gant NF, Gilstrap LC III, eds. Williams Obstetrics . 19th ed. Baltimore, Md: Williams & Wilkins;1993;:995-996.
Gregory GA, Gooding CA, Phibbs RH. Tooley WH.  Meconium aspiration in infants: a prospective study . J Pediatr . 1974;;85:848-852.
Murphy JD, Vawter GF, Reid LM.  Pulmonary vascular disease in fatal meconium aspiration . J Pediatr . 1984;;104:758-762.
Cunningham AS, Lawson EE, Martin RJ, Pildes RS.  Tracheal suction and meconium: a proposed standard of care . J Pediatr . 1990;;116:153-154.
Stocker JT, Dehner LP. Pediatric Pathology . Philadelphia, Pa: JB Lippincott Co; 1992;:545.
Yuksel B, Greenough A, Gamsu HR.  Neonatal meconium aspiration syndrome and respiratory morbidity during infancy . Pediatr Pulmonol . 1993;;16:358-361.

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