The fourth edition of this book continues to maintain a high standard of exposition and lucidity. When confronted with over 1000 pages, I do not attempt to read each page because by doing so I might have the fifth edition to review next. I did read carefully 2 types of sections: those where I am already knowledgeable by virtue of experience and interest (diarrheal disease and nutrition) and several where my experience is minimal and my knowledge probably out-of-date (pancreatic disorders, liver transplantation, and parasites). I found both types of chapters very well done. The chapter on diarrheal disease was not only comprehensive but clearly written and strong on pathogenesis and mechanism beyond what one would expect in a book with "clinical" in the title. Except for the vexing, although traditional, habit of calling the infectious enteritides gastroenteritis (almost none of the common agents produce gastritis), I have only admiration.