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An Unusual Presentation of Erythema Toxicum Scrotal Pustules Present at Birth

Frank A. Maffei, MD; Marian G. Michaels, MD, MPH; Ellen R. Wald, MD
Arch Pediatr Adolesc Med. 1996;150(6):649-650. doi:10.1001/archpedi.1996.02170310083017.
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Erythema toxicum neonatorum is the most common dermatological condition of the newborn period with an incidence of 30% to 70%.1-3 Metlinger described the rash as early as the 15th century.4 It is a benign eruption with a variable presentation that has been reported to occur at lower incidence with diminishing gestational age and birth weight.5 The precise cause of the rash is unknown; however, proposals range from an allergic phenomenon to mechanical or chemical irritation.2,6 The rash may be present at birth7 but more commonly appears on day of life 2 to 4.8 It consists of pale yellow to white papules or pustules on an irregular erythematous base; it has been described as having a "flea-bitten appearance."9 Lesions can be found on any part of the body, although palms and soles are usually spared. There are no systemic findings except blood eosinophilia; counts

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