Pseudomonas aeruginosa is an opportunistic pathogen that may cause severe infections in neonatal units.1 This pathogen has been grown from sites such as the respiratory, genitourinary, and digestive tracts, and colonization of the gastrointestinal tract has been documented frequently in new-borns.2 However, its clinical relevance has not been totally clarified. Although many neonatologists regard the recovery of P aeruginosa from stool of neonates as nonsignificant, there have been several reports that associated P aeruginosa recovery from stool with symptomatic and even serious states of the gastrointestinal tract.3
To investigate the clinical relevance of P aeruginosa stool growth in neonates, we initiated the following study.
Material and Methods. We collected stool samples from neonates hospitalized at the neonatal intensive care unit of the Edith Wolfson Medical Center, Holon, Israel, from January 1992 to July 1992. Neonates admitted to this unit were premature or suffered from an underlying illness.