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Is Underimmunization a Marker for Insufficient Utilization of Preventive and Primary Care? FREE

Lance E. Rodewald, MD; Peter G. Szilagyi, MD, MPH; Timothy Shiuh; Sharon G. Humiston, MD, MPH; Charles LeBaron, MD; Caroline B. Hall, MD
Arch Pediatr Adolesc Med. 1995;149(4):393-397. doi:10.1001/archpedi.1995.02170160047007.
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Objective:  To test the hypothesis that the underimmunization of young children is a marker for the lack of preventive and acute primary care.

Setting:  Primary care center serving an impoverished population (90% Medicaid).

Design:  Historical cohort study (N=1178) of children aged 12 to 30 months that determined each child's immunization status; anemia, tuberculosis, and lead screening status; and office utilization history. Screening delay was defined as missing a recommended screening by more than 3 months past the standard screening age.

Results:  Thirty-four percent of the population were underimmunized at 12 months of age. Compared with fully immunized children, these children were at greater risk for screening delay: anemia, 38% vs 5% (risk ratio [RR], 7.5; 95% confidence interval [CI], 5.4 to 10.4); tuberculosis, 76% vs 44% (RR, 1.7; CI, 1.6 to 1.9); and lead, 69% vs 33% (RR, 2.1; CI, 1.9 to 2.4). These RRs increased with greater immunization delay. Compared with fully immunized children, the underimmunized group made 47% fewer preventive health visits (2.5 vs 4.7 visits per infant per year, P<.001) and 43% fewer illness visits (2.5 vs 4.4, P<.001) and had 50% more missed appointments (2.1 vs 1.4, P<.001). Logistic regression, predicting anemia screening delay at 12 months of age, showed that underimmunization had an effect independent of utilization, with an odds ratio of 7.7 (CI, 5.2 to 12.0).

Conclusion:  Underimmunization was a powerful, independent marker for inadequate health supervision in this population.

Implications:  The current emphasis on immunizations has the benefit of targeting children at risk of lack of preventive and acute care. Improving immunization rates may have the potential to improve other aspects of primary care if immunization provision is not uncoupled from primary care.(Arch Pediatr Adolesc Med. 1995;149:393-397)

REFERENCES

Centers for Disease Control.  Progress toward achieving the national 1990 objectives for immunization . MMWR Morb Mortal Wkly Rep . 1988;;37:613-617.
Orenstein WA, Bernier RH.  Surveillance: information for action . Pediatr Clin North Am . 1990;;37:709-734.
Cutts FT, Zell ER, Mason D, et al.  Monitoring progress toward US preschool immunization goals . JAMA . 1992;;267:1952-1955.
Centers for Disease Control.  Measles vaccination levels among selected groups of preschool-aged children—United States . MMWR Morb Mortal Wkly Rep . 1991;;40:36-39.
Centers for Disease Control.  Retrospective assessment of vaccination coverage among school-aged children—selected US cities, 1991 . MMWR Morb Mortal Wkly Rep . 1992;;41:103-107.
National Vaccine Advisory Committee.  The measles epidemic: the problems, barriers, and recommendations . JAMA . 1991;;266:1547-1552.
Centers for Disease Control and Prevention.  Measles—United States 1992 . MMWR Morb Mortal Wkly Rep . 1993;;42:378-381.
Williams BC.  Immunization coverage among preschool children: the United States and selected European countries . Pediatrics . 1990;;86( (suppl 2) ):1052-1056.
Marks JS, Halpin TJ, Irvin JJ, et al.  Risk factors associated with failure to receive vaccinations . Pediatrics . 1979;;64:304-309.
Newacheck PW, Halfon N.  Preventive care use by school-aged children: differences by socioeconomic status . Pediatrics . 1988;;82;462-468.
US Department of Health and Human Services. Healthy People 2000 . Washington, DC: US Dept of Health and Human Services; 1990;.
Institute of Medicine. Overcoming Barriers to Immunization . Washington, DC: National Academy Press; 1994;.
Committee on Infectious Diseases, American Academy of Pediatrics. Report of the Committee on Infectious Diseases . Elk Grove Village, III: American Academy of Pediatrics; 1991;.
Raubertas RF, Rodewald LE, Humiston SG, Szilagyi PG. Defining and measuring undervaccination. In: Proceedings of the 25th National Immunization Conference. Washington, DC: Centers for Disease Control, National Center for Prevention Services; 1991:171-172.
Cornfield J.  A statistical problem arising from retrospective studies . In: Neyman J, ed. Proceedings of the Third Berkeley Symposium on Mathematical Statistics and Probability . Berkeley: University of California Press; 1956;;4:135-148.
Fielding JE, Cumberlant WG, Pettitt L.  Immunization status of children of employees in a large corporation . JAMA . 1994;;271:525-530.
Szilagyi PG, Rodewald LE, Humiston SG, et al.  Missed opportunities for childhood vaccinations in office practices and the effect on vaccination status . Pediatrics . 1993;;91:1-7.

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References

Centers for Disease Control.  Progress toward achieving the national 1990 objectives for immunization . MMWR Morb Mortal Wkly Rep . 1988;;37:613-617.
Orenstein WA, Bernier RH.  Surveillance: information for action . Pediatr Clin North Am . 1990;;37:709-734.
Cutts FT, Zell ER, Mason D, et al.  Monitoring progress toward US preschool immunization goals . JAMA . 1992;;267:1952-1955.
Centers for Disease Control.  Measles vaccination levels among selected groups of preschool-aged children—United States . MMWR Morb Mortal Wkly Rep . 1991;;40:36-39.
Centers for Disease Control.  Retrospective assessment of vaccination coverage among school-aged children—selected US cities, 1991 . MMWR Morb Mortal Wkly Rep . 1992;;41:103-107.
National Vaccine Advisory Committee.  The measles epidemic: the problems, barriers, and recommendations . JAMA . 1991;;266:1547-1552.
Centers for Disease Control and Prevention.  Measles—United States 1992 . MMWR Morb Mortal Wkly Rep . 1993;;42:378-381.
Williams BC.  Immunization coverage among preschool children: the United States and selected European countries . Pediatrics . 1990;;86( (suppl 2) ):1052-1056.
Marks JS, Halpin TJ, Irvin JJ, et al.  Risk factors associated with failure to receive vaccinations . Pediatrics . 1979;;64:304-309.
Newacheck PW, Halfon N.  Preventive care use by school-aged children: differences by socioeconomic status . Pediatrics . 1988;;82;462-468.
US Department of Health and Human Services. Healthy People 2000 . Washington, DC: US Dept of Health and Human Services; 1990;.
Institute of Medicine. Overcoming Barriers to Immunization . Washington, DC: National Academy Press; 1994;.
Committee on Infectious Diseases, American Academy of Pediatrics. Report of the Committee on Infectious Diseases . Elk Grove Village, III: American Academy of Pediatrics; 1991;.
Raubertas RF, Rodewald LE, Humiston SG, Szilagyi PG. Defining and measuring undervaccination. In: Proceedings of the 25th National Immunization Conference. Washington, DC: Centers for Disease Control, National Center for Prevention Services; 1991:171-172.
Cornfield J.  A statistical problem arising from retrospective studies . In: Neyman J, ed. Proceedings of the Third Berkeley Symposium on Mathematical Statistics and Probability . Berkeley: University of California Press; 1956;;4:135-148.
Fielding JE, Cumberlant WG, Pettitt L.  Immunization status of children of employees in a large corporation . JAMA . 1994;;271:525-530.
Szilagyi PG, Rodewald LE, Humiston SG, et al.  Missed opportunities for childhood vaccinations in office practices and the effect on vaccination status . Pediatrics . 1993;;91:1-7.

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