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Establishing Clinically Relevant Standards for Tachypnea in Febrile Children Younger Than 2 Years FREE

James A. Taylor, MD; Mark Del Beccaro, MD; Stephen Done, MD; William Winters, MD
Arch Pediatr Adolesc Med. 1995;149(3):283-287. doi:10.1001/archpedi.1995.02170150063011.
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Objective:  To determine values for defining tachypnea in febrile children younger than 2 years that best identify those at risk for pneumonia.

Design:  Prospective case series.

Study Patients:  Children younger than 2 years presenting to the emergency department of a children's hospital with a temperature of 38°C or higher.

Interventions:  Using a standardized method, respiratory rates were obtained on eligible children for 1 year. Study patients were classified as having pneumonia or no pneumonia based on clinical evaluation and chest radiograph findings. Receiver operating characteristic curves were constructed to select the values for respiratory rate that maximized sensitivity and specificity of tachypnea as a sign of pneumonia.

Results:  Data were analyzed for 572 children; pneumonia was present in 42 (7%). The diagnostic utility of tachypnea was maximal when cutoff values for respiratory rates of 59/min in infants younger than 6 months, 52/min in those aged 6 through 11 months, and 42/min in those aged 1 to 2 years were selected. Based on these definitions, tachypnea as a sign of pneumonia had a sensitivity of 73.8%, specificity of 76.8%, positive predictive value of 20.1%, and negative predictive value of 97.4%.

Conclusions:  Tachypnea, as defined in this study, is an important predictive sign of pneumonia in febrile children younger than 2 years. Conversely, the absence of tachypnea obviates the need for chest radiography in most settings.(Arch Pediatr Adolesc Med. 1995;149:283-287)

REFERENCES

Leventhal JM.  Clinical predictors of pneumonia as a guide to ordering chest roentgenograms . Clin Pediatr . 1982;;21:730-734.
Iliff A, Lee VA.  Pulse rate, respiratory rate, and body temperature of children between 2 months and 18 years of age . Child Dev . 1952;;23:237-245.
Morley CJ, Thornton AJ, Fowler MA, Cole TJ, Hewson PH.  Respiratory rate and severity of illness in babies under 6 months old . Arch Dis Child . 1990;; 65:834-837.
Cohen J.  Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit . Psychol Bull . 1968;;70:213-220.
Cherian T, John TJ, Simoes E, Steinhoff M, John M.  Evaluation of simple clinical signs for the diagnosis of acute respiratory tract infection . Lancet . 1988;; ii:125-128.
Mulholland EK, Simoes EA, Costales MO, McGrath EJ, Manalac EM, Gove S.  Standardized diagnosis of pneumonia in developing countries . Pediatr Infect Dis J . 1992;;11:77-81.
Gadomski AM.  Correcting respiratory rate (RR) for the presence of fever . AJDC . 1992;:46:493.
Simoes EA, Roark R, Berman S, Esler LL, Murphy J.  Respiratory rate: measurement of variability over time and accuracy at different counting periods . Arch Dis Child . 1991;;66:1199-1203.
Patterson RJ, Bisset GS, Kirks DR, Vanessa A.  Chest radiographs in the evaluation of the febrile infant . AJR Am J Roentgenol . 1990;;155:833-835.
McCarthy PL, Jekel JF, Dolan TF Jr.  Temperature greater than or equal to 40°C in children less than 24 months of age: a prospective study . Pediatrics . 1977;; 59:663-668.
Crain EF, Bulas D, Bijur PE, Goldman HS.  Is a chest radiograph necessary in the evaluation of every febrile infant less than 8 weeks of age? Pediatrics . 1991;; 88:821-824.

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References

Leventhal JM.  Clinical predictors of pneumonia as a guide to ordering chest roentgenograms . Clin Pediatr . 1982;;21:730-734.
Iliff A, Lee VA.  Pulse rate, respiratory rate, and body temperature of children between 2 months and 18 years of age . Child Dev . 1952;;23:237-245.
Morley CJ, Thornton AJ, Fowler MA, Cole TJ, Hewson PH.  Respiratory rate and severity of illness in babies under 6 months old . Arch Dis Child . 1990;; 65:834-837.
Cohen J.  Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit . Psychol Bull . 1968;;70:213-220.
Cherian T, John TJ, Simoes E, Steinhoff M, John M.  Evaluation of simple clinical signs for the diagnosis of acute respiratory tract infection . Lancet . 1988;; ii:125-128.
Mulholland EK, Simoes EA, Costales MO, McGrath EJ, Manalac EM, Gove S.  Standardized diagnosis of pneumonia in developing countries . Pediatr Infect Dis J . 1992;;11:77-81.
Gadomski AM.  Correcting respiratory rate (RR) for the presence of fever . AJDC . 1992;:46:493.
Simoes EA, Roark R, Berman S, Esler LL, Murphy J.  Respiratory rate: measurement of variability over time and accuracy at different counting periods . Arch Dis Child . 1991;;66:1199-1203.
Patterson RJ, Bisset GS, Kirks DR, Vanessa A.  Chest radiographs in the evaluation of the febrile infant . AJR Am J Roentgenol . 1990;;155:833-835.
McCarthy PL, Jekel JF, Dolan TF Jr.  Temperature greater than or equal to 40°C in children less than 24 months of age: a prospective study . Pediatrics . 1977;; 59:663-668.
Crain EF, Bulas D, Bijur PE, Goldman HS.  Is a chest radiograph necessary in the evaluation of every febrile infant less than 8 weeks of age? Pediatrics . 1991;; 88:821-824.

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