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Hüseyin Güvenc, MD; A. Denizmen Aygün, MD; Kenan Kocabay, MD; Dursun Türkbay, MD; Walter W. Tunnessen Jr, MD
Arch Pediatr Adolesc Med. 1994;148(10):1065-1066. doi:10.1001/archpedi.1994.02170100063012.
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Denouement and Discussion 

Turner's Syndrome 

MANIFESTATIONS  Henry Hubert Turner, American endocrinologist, described a syndrome marked by short stature, sexual infantilism, webbed neck, and cubitus valgus in adult females in 1938. Ullrich, in 1930, and Bonnevie, in 1934, described neonates with lymphedema of the hands and feet and pterygium colli, which were later believed to be manifestations of the same syndrome.1 The chromosomal abnormalities associated with Turner's syndrome were first described in 1959.Lymphedema of the dorsa of the hands and feet and loose skin folds at the nape of the neck are characteristic of this syndrome and, when present, should direct attention to other associated features. Lymphedema is present in about one third of infants. Affected newborns tend to be small, with a mean birth weight of 2900 g. The chest appears broad, giving the illusion of widely spaced nipples.1There is wide phenotypic variability in the appearance of


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