0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Brucellosis Presenting as Prolonged Fever and Hemophagocytosis

CARI H. ULLRICH, MD; ROBERT FADER, PHD; JAMES B. FAHNER, MD; STEPHEN D. BARBOUR, MD, PHD
Am J Dis Child. 1993;147(10):1037-1038. doi:10.1001/archpedi.1993.02160340023005.
Text Size: A A A
Published online

Sir.—Brucellosis is an infectious disease caused by a gram-negative coccobacillus passed from animals to humans by airborne spread, direct contact, and ingestion of infectious animal products. Infections with the species Brucella melitensis, associated with ingestion of contaminated goat and sheep milk products, are among the most invasive.1 Brucellosis is unusual in US children, accounting for fewer than 10% of reported US cases.2 Outbreaks are rare in brucellosis-free states, and Michigan had been brucellosis free since 1980.3 We describe aningestion-associated outbreak of B melitensis infections that initially presented in a 15-year-old patient with prolonged fever and hemophagocytosis.

Patient Report.—A previously healthy 15-year-old Hispanic boy presented with a 3-week history of fever, fatigue, weight Photomicrograph of bone marrow aspirate from the 15-year-old index patient demonstrating large activated histiocytes and erythrophagocytosis. loss, myalgias, lumbosacral pain, blurred vision, and epistaxis. Physical examination revealed mild hepatomegaly and a tender spleen

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();