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Are Children Born Small for Gestational Age at Increased Risk of Short Stature? FREE

Ido Paz, MD; Daniel S. Seidman, MD; Yehuda L. Danon, MD; Arie Laor, MD, MSc; David K. Stevenson, MD; Rena Gale, MD
[+] Author Affiliations

Accepted for publication October 19, 1992.

Presented in part at the annual meeting of the Society for Pediatric Research, Baltimore, Md, May 6, 1992.

Reprints not available.


Am J Dis Child. 1993;147(3):337-339. doi:10.1001/archpedi.1993.02160270099030.
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• Objective.  —To assess the height outcome of newborns born small for gestational age.

Design.  —A historical prospective study.

Setting.  —A cohort of 1758 newborns born at a single university hospital maternity ward and subsequently examined at the military draft medical board at age 17 years.

Participants.  —Newborns whose weight at birth was below the third percentile were defined as small for gestational age. Their body measurements at age 17 years were compared with those of their peers who were appropriate for gestational age.

Measurements/Main Results.  —The adjusted mean ± SEM height for boys born small for gestational age vs peers born appropriate for gestational age was 169.9±1.5 vs 175.4±0.8 cm (P<.0001); and for girls, 159.4±1.3 vs 163.1 ±0.8 cm (P<.0005). In addition, the risk for height attainment below the 10th percentile was significantly increased for newborns born small for gestational age. The adjusted odds ratio was 4.13 for boys (95% confidence interval, 1.66 to 10.25; P<.0006) and 3.32 for girls (95% confidence interval, 1.38 to 8.05; P<.0005).

Conclusion.  —Infants born small for gestational age may be at increased risk for short stature in late adolescence.(AJDC. 1993;147:337-339)

REFERENCES

Teberg AJ, Walther FJ, Pena IC.  Morbidity, mortality and outcome of the small for gestational age infant . Semin Perinatol . 1988;;12:84-94.
Fitzhardinge PM, Inwood S.  Long-term growth in small for date children . Acta Paediatr Scand. 1989;;349:27-33.
Hadders-Algra M, Touwen BCL.  Body measurements, neurological and behavioral development in six-year-old children born preterm and/or small for generational age . Early Hum Dev. 1990;;22:1-13.
Westwood M, Kramer MS, Munz D, Lovett JM, Watters GV.  Growth and development of full-term non-asphyxiated small for gestational age infants . Pediatrics . 1983;;71:376-382.
Low JA, Galbriath RS, Muir D, Killen H, Pater B, Karchmar J.  Intrauterine growth retardation: a study of long-term morbidity . Am J Obstet Gynecol . 1982;;142:670-677.
Harlap S, Davies AM, Grover NB, Prywes R.  The Jerusalem Perinatal Study: the first decade 1964-1973 . Isr J Med Sci. 1977;;13:1073-1082.
Lubchenco LO, Hansman C, Boyd E.  Intrauterine growth in length and head circumference as estimated from live birth at gestational ages from 26 to 42 weeks . Pediatrics . 1966;;37:403-408.
Winick M.  Malnutrition and brain development . J Pediatr. 1969;;74:667.
Laor A, Seidman DS, Danon YL.  Changes in body height among selected ethnic groups . J Epidemiol Community Health . 1991;;45:169-170.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Teberg AJ, Walther FJ, Pena IC.  Morbidity, mortality and outcome of the small for gestational age infant . Semin Perinatol . 1988;;12:84-94.
Fitzhardinge PM, Inwood S.  Long-term growth in small for date children . Acta Paediatr Scand. 1989;;349:27-33.
Hadders-Algra M, Touwen BCL.  Body measurements, neurological and behavioral development in six-year-old children born preterm and/or small for generational age . Early Hum Dev. 1990;;22:1-13.
Westwood M, Kramer MS, Munz D, Lovett JM, Watters GV.  Growth and development of full-term non-asphyxiated small for gestational age infants . Pediatrics . 1983;;71:376-382.
Low JA, Galbriath RS, Muir D, Killen H, Pater B, Karchmar J.  Intrauterine growth retardation: a study of long-term morbidity . Am J Obstet Gynecol . 1982;;142:670-677.
Harlap S, Davies AM, Grover NB, Prywes R.  The Jerusalem Perinatal Study: the first decade 1964-1973 . Isr J Med Sci. 1977;;13:1073-1082.
Lubchenco LO, Hansman C, Boyd E.  Intrauterine growth in length and head circumference as estimated from live birth at gestational ages from 26 to 42 weeks . Pediatrics . 1966;;37:403-408.
Winick M.  Malnutrition and brain development . J Pediatr. 1969;;74:667.
Laor A, Seidman DS, Danon YL.  Changes in body height among selected ethnic groups . J Epidemiol Community Health . 1991;;45:169-170.

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