A 3-month-old girl who was born prematurely was transferred to our facility for cryotherapy because of retinopathy of prematurity. She had been born at 23 weeks' gestation and weighed 745 g. Results of admission physical examination were remarkable for an elongated head with a high cranial vault, frontal bossing, and saddle deformity of the nose. Her head circumference was 38.5 cm, the anterior fontanelle was open, and there was a palpable midline ridge over the sagittal area. A three-dimensional computed tomogram was obtained (Fig 1).
An infant boy born after a full-term pregnancy and weighing 3285 g at birth was transferred to our facility because of multiple congenital anomalies, which included a cleft lip, syndactyly, cryptorchidism, a ventricular septal defect, and vertebral anomalies. His head circumference was 34 cm (in the 60th percentile for his age). His head was asymmetric, with flattening of the right occiput, and his