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July 1992, Vol 146, No. 7 >
Article | July 1992

Iron State in Female Adolescents FREE

Ami Ballin, MD; Michael Berar, MD; Uri Rubinstein, MD; Yesheayahu Kleter, MD; Ariela Hershkovitz, Mgr; Dina Meytes, MD
[+] Author Affiliations

Accepted for publication November 27, 1991.

Reprint requests to the Institute of Haematology, E. Wolfson Hospital, Holon 58100, Tel Aviv, Israel (Dr Ballin).


Am J Dis Child. 1992;146(7):803-805. doi:10.1001/archpedi.1992.02160190035015.
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• Objective.  —To document a subjective response to iron therapy in female adolescents.

Design.  —Double-blind, placebo-controlled prospective study.

Setting.  —High school classes in an urban community in Israel.

Participants.  —Twenty-nine girls, aged 16 and 17 years, who ingested syrup containing iron (daily for 2 months) and 30 girls who received a placebo.

Main Results.  —By the end of the study, a statistically significant improvement in three subjective parameters, ie, lassitude, the ability to concentrate in school, and mood was reported by the girls who ingested iron compared with the controls. Sixty-five percent, 100%, and 65% of the girls, respectively, who reported improvement in the abovementioned parameters were hypoferremic initially and became normoferremic by the end of the study.

Conclusion.  —Iron supplementation may be of benefit to female adolescents, as evidenced by their responses to subjective parameters.(AJDC. 1992;146:803-805)

REFERENCES

1 +
Dallman PR.  Iron deficiency and related nutritional anemias . In: Nathan DG, Oski FA, eds. Hematology of Infancy and Childhood . Philadelphia, Pa: WB Saunders Co; 1987;:276-285.
2 +
Cook JD, Finch CA, Smith NJ.  Evaluation of the iron status of a population . Blood . 1976;;48:449-455.
3 +
Cook JD, Finch CA.  Assessing iron status of a population . Am J Clin Nutr . 1979;;32:2115-2119.
4 +
Dallman PR, Yip R, Johnson C.  Prevalence and causes of anemia in the United States, 1976-1980 . Am J Clin Nutr . 1984;;39:437-445.
5 +
Lozoff B, Brittenham GM, Wolf AW, et al.  Iron deficiency anemia and iron therapy effects on infant development test performance . Pediatrics . 1987;;79:981-995.
6 +
Rowland TW, Deisroth MB, Green GM, Kelleher JF.  The effect of iron therapy on the exercise capacity of nonanemic iron-deficient adolescent runners . AJDC . 1988;;142:165-169.
7 +
Edgerton VR, Gardner GW, Ohira Y, Gunawardena KA, Senewiratne B.  Iron-deficiency anaemia and its effect on worker productivity and activity patterns . BMJ . 1979;;2:1546-1549.
8 +
Schone RB, Escererrou P, Robertson HT.  Iron repletion decreases maximal exercise lactate concentration in female athletes with minimal iron-deficient anemia . J Lab Clin Med . 1983;;102:306-312.
9 +
Walter T, De Andraca I, Chadud P, Perales CG.  Iron deficiency anemia: adverse effects on infant psychomotor development . Pediatrics . 1989;;84:7-17.
10 +
Walter T, Kovalskys J, Stekel A.  Effect of mild iron deficiency on infant mental development scores . J Pediatr . 1983;;102:519-522.
11 +
Oski FA, Honig AS, Helu B, Howanitz P.  Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants . Pediatrics . 1983;;71:877-880.
12 +
Soemantri AG, Pollit E, Kim I.  Iron deficiency anemia and educational achievement . Am J Clin Nutr . 1985;;42:1221-1228.
13 +
Pollitt E, Soemantri AG, Yunis F.  Cognitive effects of irondeficiency anemia . Lancet . 1985;;1:158.
14 +
Seshadri S, Hirode K, Naik P, et al.  Behavioral responses of young anemic Indian children to iron folic acid supplements . Br J Nutr . 1982;;48:233-240.
15 +
Dallman PR, siimes MA, Stekel A.  Iron deficiency in infancy and childhood . Am J Clin Nutr . 1980;;33:86-118.
16 +
Groner JA, Holtzman NA, Charmey E, et al.  A randomized trial of oral iron on tests of short-term memory and attention span in young pregnant women . J Adolesc Health Care . 1986;;7:44-48.
17 +
Scott DE, Pritchard JA.  Iron deficiency in healthy young college women . JAMA . 1987;;199:897-900.
18 +
Thompson WG.  Comparison of tests for diagnosis of iron depletion in pregnancy . Am J Obstet Gynecol . 1988;;159:1132-1134.
19 +
American Academy of Pediatrics, Committee on Nutrition.  Iron supplementation for infants . Pediatrics . 1976;;58:765-768.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Dallman PR.  Iron deficiency and related nutritional anemias . In: Nathan DG, Oski FA, eds. Hematology of Infancy and Childhood . Philadelphia, Pa: WB Saunders Co; 1987;:276-285.
2 +
Cook JD, Finch CA, Smith NJ.  Evaluation of the iron status of a population . Blood . 1976;;48:449-455.
3 +
Cook JD, Finch CA.  Assessing iron status of a population . Am J Clin Nutr . 1979;;32:2115-2119.
4 +
Dallman PR, Yip R, Johnson C.  Prevalence and causes of anemia in the United States, 1976-1980 . Am J Clin Nutr . 1984;;39:437-445.
5 +
Lozoff B, Brittenham GM, Wolf AW, et al.  Iron deficiency anemia and iron therapy effects on infant development test performance . Pediatrics . 1987;;79:981-995.
6 +
Rowland TW, Deisroth MB, Green GM, Kelleher JF.  The effect of iron therapy on the exercise capacity of nonanemic iron-deficient adolescent runners . AJDC . 1988;;142:165-169.
7 +
Edgerton VR, Gardner GW, Ohira Y, Gunawardena KA, Senewiratne B.  Iron-deficiency anaemia and its effect on worker productivity and activity patterns . BMJ . 1979;;2:1546-1549.
8 +
Schone RB, Escererrou P, Robertson HT.  Iron repletion decreases maximal exercise lactate concentration in female athletes with minimal iron-deficient anemia . J Lab Clin Med . 1983;;102:306-312.
9 +
Walter T, De Andraca I, Chadud P, Perales CG.  Iron deficiency anemia: adverse effects on infant psychomotor development . Pediatrics . 1989;;84:7-17.
10 +
Walter T, Kovalskys J, Stekel A.  Effect of mild iron deficiency on infant mental development scores . J Pediatr . 1983;;102:519-522.
11 +
Oski FA, Honig AS, Helu B, Howanitz P.  Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants . Pediatrics . 1983;;71:877-880.
12 +
Soemantri AG, Pollit E, Kim I.  Iron deficiency anemia and educational achievement . Am J Clin Nutr . 1985;;42:1221-1228.
13 +
Pollitt E, Soemantri AG, Yunis F.  Cognitive effects of irondeficiency anemia . Lancet . 1985;;1:158.
14 +
Seshadri S, Hirode K, Naik P, et al.  Behavioral responses of young anemic Indian children to iron folic acid supplements . Br J Nutr . 1982;;48:233-240.
15 +
Dallman PR, siimes MA, Stekel A.  Iron deficiency in infancy and childhood . Am J Clin Nutr . 1980;;33:86-118.
16 +
Groner JA, Holtzman NA, Charmey E, et al.  A randomized trial of oral iron on tests of short-term memory and attention span in young pregnant women . J Adolesc Health Care . 1986;;7:44-48.
17 +
Scott DE, Pritchard JA.  Iron deficiency in healthy young college women . JAMA . 1987;;199:897-900.
18 +
Thompson WG.  Comparison of tests for diagnosis of iron depletion in pregnancy . Am J Obstet Gynecol . 1988;;159:1132-1134.
19 +
American Academy of Pediatrics, Committee on Nutrition.  Iron supplementation for infants . Pediatrics . 1976;;58:765-768.

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