Sir.—Kawasaki disease is a vasculitis of unknown etiology. It is usually accompanied by a febrile illness and occurs primarily in infancy and early childhood. Numerous associated clinical manifestations have been described. Reported mucocutaneous abnormalities have included oropharyngeal changes, polymorphous rash, and peripheral extremity changes. The latter have included erythema of the palms and soles, induration of the hands and feet, desquamation of the skin of the hands and feet, and Beau's lines.1 Unusual red transverse nail-bed lines were observed in four of our patients with Kawasaki disease. No previous report of this clinical manifestation was found.
Patients and Methods.—All patients fulfilled classic diagnostic criteria of Kawasaki disease and were seen by the author between 1984 and 1990 either in the Pediatric Arthritis Clinic at the University of Kansas Medical Center or during inpatient consultations.2
Results.—Four of the 26 patients demonstrated red transverse nail-bed lines (Figure).