0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Antibody Response to MMR Vaccination in Children Who Received IVIG as Neonates

JEANNE W. RUDERMAN, MD; NOORI BARKA, PHD; JAMES B. PETER, MD, PHD; E. RICHARD STIEHM, MD
Am J Dis Child. 1991;145(4):425-426. doi:10.1001/archpedi.1991.02160040081007.
Text Size: A A A
Published online

Sir.—The administration of intravenous immunoglobulin (IVIG) to

neonates has few or no acute short-term effects,1 but less is known about the subsequent effect on humoral immune function. We studied the response to measles, mumps, rubella (MMR) vaccination in five children who received multiple infusions of IVIG during the neonatal period.

We obtained serum from five children who had participated in a study of IVIG pharmakokinetics in infants of 32 weeks' gestation or less weighing 1500 g or less in the Cedars-Sinai Neonatal Intensive Care Unit, Los Angeles, Calif.2 The Table shows the gestational age and birth weight of each infant, the number of IVIG infusions, and total IVIG dose. These infants were subsequently vaccinated against rubeola, mumps, and rubella at 15 months of age. Serum samples were obtained 2 months after vaccination. The Table also shows the IgG response to MMR vaccination with reference ranges. Following

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();