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Mediterranean Spotted Fever in Children Returning From France FREE

Thomas L. Treadwell, MD; Scott D. Phillips, MD; William J. Jablonski, MD
[+] Author Affiliations

Accepted for publication November 9, 1989.

Reprint requests to Framingham Union Hospital, 115 Lincoln St, Framingham, MA 01701 (Dr Treadwell).


Am J Dis Child. 1990;144(9):1037-1038. doi:10.1001/archpedi.1990.02150330097030.
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• Although the incidence of Mediterranean spotted fever has increased dramatically in parts of Europe, Africa, and Asia, the disease is only rarely seen in travelers. We describe two children who had traveled in southern France and subsequently had rash and lymphadenopathy develop. Both children were treated with doxycycline and had unequivocal serologic evidence of Mediterranean spotted fever develop. Although this disease is usually mild, in the absence of a tick bite the disease can easily be confused with other febrile exanthems. We describe these patients to reemphasize the influence that international travel has brought to pediatrics.

(AJDC. 1990;144:1037-1038)

REFERENCES

Font-Creus B, Bella-Cueto F, Espejo-Arenas E, et al.  Mediterranean spotted fever: a cooperative study of 227 cases . Rev Infect Dis . 1985;;7:635-642.
Anderson J, Magnarelli L, Burgdorfer W, et al.  Importation into the United States from Africa of Rhipicephalus simus on a Boutonneuse fever patient . Am J Trop Med Hyg . 1981;;30:897-899.
Barrett-Connor E, Ginsberg M.  Imported South African tick typhus . West J Med . 1983;;138:264-266.
Moraga F, Martinez-Roig A, Alonso J, et al.  Boutonneuse fever . Arch Dis Child . 1982;;57:149-151.
Raoult D, deMicco C, Gallais H, et al.  Laboratory diagnosis of Mediterranean spotted fever by immunofluorescent demonstration of Rickettsia conorii in cutaneous lesions . J Infect Dis . 1984;; 150:145-148.
Huys J, Freyens P, Kayihigi J, et al.  Treatment of epidemic typhus: a comparative study of chloramphenicol, trimethoprim-sulfamethoxazole, and doxycycline . Trans R Soc Trop Med Hyg . 1973;; 67:718-721.
Tringali G, Intonazzo V, Perna A, et al.  Epidemiology of Boutonneuse fever in western Sicily . Am J Epidemiol . 1986;;123:721-727.

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References

Font-Creus B, Bella-Cueto F, Espejo-Arenas E, et al.  Mediterranean spotted fever: a cooperative study of 227 cases . Rev Infect Dis . 1985;;7:635-642.
Anderson J, Magnarelli L, Burgdorfer W, et al.  Importation into the United States from Africa of Rhipicephalus simus on a Boutonneuse fever patient . Am J Trop Med Hyg . 1981;;30:897-899.
Barrett-Connor E, Ginsberg M.  Imported South African tick typhus . West J Med . 1983;;138:264-266.
Moraga F, Martinez-Roig A, Alonso J, et al.  Boutonneuse fever . Arch Dis Child . 1982;;57:149-151.
Raoult D, deMicco C, Gallais H, et al.  Laboratory diagnosis of Mediterranean spotted fever by immunofluorescent demonstration of Rickettsia conorii in cutaneous lesions . J Infect Dis . 1984;; 150:145-148.
Huys J, Freyens P, Kayihigi J, et al.  Treatment of epidemic typhus: a comparative study of chloramphenicol, trimethoprim-sulfamethoxazole, and doxycycline . Trans R Soc Trop Med Hyg . 1973;; 67:718-721.
Tringali G, Intonazzo V, Perna A, et al.  Epidemiology of Boutonneuse fever in western Sicily . Am J Epidemiol . 1986;;123:721-727.

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