0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Atrioventricular Canal Without Down Syndrome Associated With Additional Cardiac and Noncardiac Anomalies

BRUNO MARINO, MD; PAOLO GUCCIONE, MD; CARLO MARCELLETTI, MD; BRUNO DALLAPICCOLA, MD
Am J Dis Child. 1990;144(7):752. doi:10.1001/archpedi.1990.02150310018015.
Text Size: A A A
Published online

Sir.—We read the interesting article by Vet and Ottenkamp1 regarding the surgical correction of atrioventricular septal defect in relation to the presence of Down syndrome (DS) in the November 1989 issue of AJDC. This study confirms our previous observations on the prevalence of left-sided obstructive lesions in children with atrioventricular canal (AVC) without DS.2 Moreover, Vet and Ottenkamp report that "a large proportion of children without Down syndrome had other serious congenital anomalies." Our experience is in agreement with this observation. In particular, we

Two patients with "non-Down atrioventricular canal syndrome" with hypertelorism, epicanthus, and depressed nasal bridge. found a prevalence of phenotypic anomalies in "non-Down patients" with AVC.3 Comparing 75 children with AVC and 50 children with other types of congenital heart disease (all 125 with normal chromosomes), we found two or more phenotypic anomalies in 35 patients with AVC (46.6%) and only in 6

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();