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Bacterial Meningitis in Older Children FREE

William A. Bonadio, MD; Mark Mannenbach, MD; Robert Krippendorf, MD
[+] Author Affiliations

Accepted for publication September 11, 1989.

Reprint requests to 1240 Pioneer Trail, Waukesha, WI53186 (Dr Bonadio).


Am J Dis Child. 1990;144(4):463-465. doi:10.1001/archpedi.1990.02150280085016.
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• A review was performed of 25 cases of bacterial meningitis in previously healthy children aged 6 years or older during a 10-year period. The rate of infection in this age group relative to all cases of pediatric bacterial meningitis was 4%. Pathogens included Haemophilus influenzae type b in 10 cases (40%), Neisseria meningitidis in 9 cases (36%), and Streptococcus pneumoniae in 6 cases (24%). Physical findings revealed 21 patients (84%) with some degree of altered consciousness and 25 patients (100%) with nuchal rigidity. In all instances, the cerebrospinal fluid exhibited pleocytosis with a predominance of polymorphonuclear leukocytes. Eleven patients (44%) were afebrile on presentation. Of 22 surviving patients, 10 (45%) were afebrile without subsequent fever after administration of the initial dose of antibiotics, in 5 (23%) fever resolved within 24 hours, and in 6 (27%) fever resolved within 48 hours of treatment; there was no instance of prolonged or secondary fever noted. Death occurred in 3 cases (12%). Bacterial meningitis is uncommon in older children. As compared with younger children, older children with bacterial meningitis commonly present without fever and tend to have their fever resolve shortly after effective antibiotic therapy is initiated without manifesting prolonged or secondary fever patterns. Haemophilus influenzae type b is a common cause of bacterial meningitis in children aged 6 years or older; empirical antibiotic therapy in this clinical situation should include treatment of this pathogen.

(AJDC. 1990;144:463-465)

REFERENCES

Krieg AF.  Cerebrospinal fluid and other body fluids . In: Henry JB, ed. Clinical Diagnosis and Management by Laboratory Methods . 16th ed. Philadelphia, Pa: WB Saunders Co; 1981;:635-657.
Schlech WF, Ward JI, Band JD, et al.  Bacterial meningitis in the United States, 1978-1981: the National Bacterial Meningitis Surveillance Study . JAMA . 1985;;253:1749-1754.
Swartz MN, Dodge PR.  Bacterial meningitis: a review of selected aspects, I: general clinical features, special problems and unusual meningeal reactions mimicking bacterial meningitis . N Engl J Med . 1965;;272:725-731.
Del Rio M, Chrane D, Shelton S, McCracken GH, Nelson JD.  Ceftriaxone versus ampicillin and chloramphenicol for treatment of bacterial meningitis in children . Lancet . 1983;;1:1241-1244.
Feigin RD.  Bacterial meningitis beyond the newborn period . In: Feigin RD, Cherry JD, eds. Textbook of Pediatric Infectious Diseases . Philadelphia, Pa: WB Saunders Co; 1981;:293-304.
Geiseler PJ, Nelson KE.  Bacterial meningitis without signs of meningeal irritation . South Med J . 1982;;75:448-450.
Klein JO, Feigin RD, McCracken GH.  Report of the task force on diagnosis and management of meningitis . Pediatrics . 1986;;78( (suppl) ):959-982.
Stutman HR, Marks MI.  Bacterial meningitis in children: diagnosis and treatment . Clin Pediatr . 1987;;26:431-438.
Rutman DL, Wald ER.  Fever in Haemophilus influenzae type b meningitis . Clin Pediatr . 1981;;20:192-195.
Balagtas RC, Levin S, Nelson SE, Gotoff S.  Secondary and prolonged fevers in bacterial meningitis . J Pediatr . 1970;;77:957-964.
Lin TY, Nelson JD, McCracken GH.  Fever during treatment for bacterial meningitis . Pediatr Infect Dis . 1984;;3:319-322.
Dodge PR, Swartz MN.  Bacterial meningitis: a review of selected aspects, II: special neurologic problems, postmeningitic complications and clinicopathologic correlations . N Engl J Med . 1965;;272:954-960.
Lindberg J, Rosenhall U, Nylen O, Ringner A.  Long-term outcome of Haemophilus influenzae meningitis related to antibiotic treatment . Pediatrics . 1977;;60:1-6.
Dodge PR.  Sequelae of bacterial meningitis . Pediatr Infect Dis . 1986;;5:618-620.
Kaplan SL, Feigin RD.  Clinical presentations, prognostic factors and diagnosis of bacterial meningitis . In: Sande MA, Smith AL, Root RK, eds. Bacterial Meningitis . New York, NY: Churchill Livingstone Inc; 1985;:80-85.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

Krieg AF.  Cerebrospinal fluid and other body fluids . In: Henry JB, ed. Clinical Diagnosis and Management by Laboratory Methods . 16th ed. Philadelphia, Pa: WB Saunders Co; 1981;:635-657.
Schlech WF, Ward JI, Band JD, et al.  Bacterial meningitis in the United States, 1978-1981: the National Bacterial Meningitis Surveillance Study . JAMA . 1985;;253:1749-1754.
Swartz MN, Dodge PR.  Bacterial meningitis: a review of selected aspects, I: general clinical features, special problems and unusual meningeal reactions mimicking bacterial meningitis . N Engl J Med . 1965;;272:725-731.
Del Rio M, Chrane D, Shelton S, McCracken GH, Nelson JD.  Ceftriaxone versus ampicillin and chloramphenicol for treatment of bacterial meningitis in children . Lancet . 1983;;1:1241-1244.
Feigin RD.  Bacterial meningitis beyond the newborn period . In: Feigin RD, Cherry JD, eds. Textbook of Pediatric Infectious Diseases . Philadelphia, Pa: WB Saunders Co; 1981;:293-304.
Geiseler PJ, Nelson KE.  Bacterial meningitis without signs of meningeal irritation . South Med J . 1982;;75:448-450.
Klein JO, Feigin RD, McCracken GH.  Report of the task force on diagnosis and management of meningitis . Pediatrics . 1986;;78( (suppl) ):959-982.
Stutman HR, Marks MI.  Bacterial meningitis in children: diagnosis and treatment . Clin Pediatr . 1987;;26:431-438.
Rutman DL, Wald ER.  Fever in Haemophilus influenzae type b meningitis . Clin Pediatr . 1981;;20:192-195.
Balagtas RC, Levin S, Nelson SE, Gotoff S.  Secondary and prolonged fevers in bacterial meningitis . J Pediatr . 1970;;77:957-964.
Lin TY, Nelson JD, McCracken GH.  Fever during treatment for bacterial meningitis . Pediatr Infect Dis . 1984;;3:319-322.
Dodge PR, Swartz MN.  Bacterial meningitis: a review of selected aspects, II: special neurologic problems, postmeningitic complications and clinicopathologic correlations . N Engl J Med . 1965;;272:954-960.
Lindberg J, Rosenhall U, Nylen O, Ringner A.  Long-term outcome of Haemophilus influenzae meningitis related to antibiotic treatment . Pediatrics . 1977;;60:1-6.
Dodge PR.  Sequelae of bacterial meningitis . Pediatr Infect Dis . 1986;;5:618-620.
Kaplan SL, Feigin RD.  Clinical presentations, prognostic factors and diagnosis of bacterial meningitis . In: Sande MA, Smith AL, Root RK, eds. Bacterial Meningitis . New York, NY: Churchill Livingstone Inc; 1985;:80-85.

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