In Reply.—Although the sample size was small, our experience indicates that colonoscopy is useful in establishing the diagnosis of milk-induced colitis. No complications were associated with colonoscopy. Repeated milk challenges, though, may initiate severe allergic reactions.1
We feel that colonoscopy should be utilized to establish the diagnosis of milk-induced colitis. Response to therapy can be monitored using stool guaiac tests.
Three infants with eosinophilia were receiving a cow's milk formula and one infant with eosinophilia was receiving a soy protein formula. Four infants receiving cow's milk formula, one infant receiving soy formula, and one infant fed both formulas had an elevated IgE level. All the infants with a positive radioallergosorbent test were receiving a cow's milk formula.