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Gastrointestinal Milk Intolerance of Infancy-Reply

STUART BEREZIN, MD; STEVEN M. SCHWARZ, MD; MARK GLASSMAN, MD; LEONARD J. NEWMAN, MD; MARIANNA DAVIDIAN, MD
Am J Dis Child. 1990;144(1):17. doi:10.1001/archpedi.1990.02150250017015.
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In Reply.—Although the sample size was small, our experience indicates that colonoscopy is useful in establishing the diagnosis of milk-induced colitis. No complications were associated with colonoscopy. Repeated milk challenges, though, may initiate severe allergic reactions.1

We feel that colonoscopy should be utilized to establish the diagnosis of milk-induced colitis. Response to therapy can be monitored using stool guaiac tests.

Three infants with eosinophilia were receiving a cow's milk formula and one infant with eosinophilia was receiving a soy protein formula. Four infants receiving cow's milk formula, one infant receiving soy formula, and one infant fed both formulas had an elevated IgE level. All the infants with a positive radioallergosorbent test were receiving a cow's milk formula.

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