We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Correction of Atrioventricular Septal Defect Results Influenced by Down Syndrome?

Thijs W. Vet; Jaap Ottenkamp, MD
Am J Dis Child. 1989;143(11):1361-1365. doi:10.1001/archpedi.1989.02150230119039.
Text Size: A A A
Published online


• The role of Down syndrome (DS) in the outcome of the surgical correction of atrioventricular septal defect (AVSD) was investigated by the analysis of clinical events among 85 patients. Complete AVSD (cAVSD) was present in 49 patients, of whom 36 (73%) had DS. Thirty patients (83%) survived surgical treatment. Of the 13 patients without DS, 7 (54%) survived. There were four deaths and one late death. Thirty-six patients had partial AVSD (pAVSD), 5 (14%) of whom had DS; all 5 patients are still alive. Thirty (97%) of the 31 patients with pAVSD without DS survived the operation. There were two late deaths. Preoperative selection did not account for the favorable results in children with DS. All early postoperative deaths in cAVSD occurred in children younger than 2 years; low body weight for age seemed to be an important factor in adverse outcome. A large number of patients without DS had other serious congenital malformations. In view of the relatively favorable results in patients with DS, it does not seem warranted to maintain a conservative diagnostic and therapeutic approach of AVSD solely because of concomitant DS.



Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.