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Cat-scratch Disease Therapy FREE

P. J. COLLIPP, MD
Am J Dis Child. 1989;143(11):1261. doi:10.1001/archpedi.1989.02150230019008.
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Sir.—Since my original experience1 with cat-scratch disease, I have remained interested in it and impressed with its stubborn resistance to therapy.

During the last 3 months I have treated 11 children (Table) for catscratch disease with 20 mg/kg of trimethoprim-sulfamethoxazole twice daily for 7 days, and all 11 have shown prompt improvement. The enlarged nodes were visible, very tender, and firm without palpable suppuration. All of these patients were treated with trimethoprim-sulfamethoxazole twice daily within 7 days of the onset of their enlarged gland. The lymph nodes became nontender in 4 to 6 days, and smaller by 7 to 10 days. They were 10 mm or smaller by 3 weeks in all cases. Nine of 11 patients had a history of exposure to cats. There was a primary inoculation lesion (usually a scratch) in 7 of these 11 patients. My prior experience had been to treat them with

REFERENCES

Collipp PJ, Koch RA.  Cat-scratch fever associated with an osteolytic lesion . N Engl J Med . 1959;;260:278-279.
Flessner MF.  A tough diagnosis in a neutropenic patient: it's cat-scratch disease . JAMA . 1989;;261:991.
Carithers HA.  Cat-scratch disease, an overview based on a study of 1,200 patients . AJDC . 1985;;139:1124-1133.
Gerber MA, MacAlister TH, Ballow M, et al.  The aetiological agent of cat-scratch disease . Lancet . 1985;;2:1236-1239.
English CK, Wear DJ, Margileth AM.  Cat-scratch disease: isolation and culture of the bacterial agent . JAMA . 1988;;259:1347-1352.

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References

Collipp PJ, Koch RA.  Cat-scratch fever associated with an osteolytic lesion . N Engl J Med . 1959;;260:278-279.
Flessner MF.  A tough diagnosis in a neutropenic patient: it's cat-scratch disease . JAMA . 1989;;261:991.
Carithers HA.  Cat-scratch disease, an overview based on a study of 1,200 patients . AJDC . 1985;;139:1124-1133.
Gerber MA, MacAlister TH, Ballow M, et al.  The aetiological agent of cat-scratch disease . Lancet . 1985;;2:1236-1239.
English CK, Wear DJ, Margileth AM.  Cat-scratch disease: isolation and culture of the bacterial agent . JAMA . 1988;;259:1347-1352.

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