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Relation of Bone Mineralization Measures to Serum Biochemical Measures-Reply

KENNETH L. HARKAVY, MD
Am J Dis Child. 1988;142(12):1276-1277. doi:10.1001/archpedi.1988.02150120030029.
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In Reply.—I thank Dr Abrams and colleagues for bringing to my attention past and recent data regarding measurements of bone mineral and the choice of BMC or BMC/BW, in which BMC is the bone mineral content of scanned bone and BW is the width of the bone at the scan site. A recent symposium1 addressed the controversy over the relative importance of BMC and BMC/BW. While BMC may be written as milligrams per centimeter, BMC is in reality an expression of bone mineral (ash) in milligrams per square centimeter, since the measurement beam has a defined width and the scan is corrected by the absorptiometer for scan length. Also, BMC/BW is an estimate of density (g/cm3), in which BW is assumed to represent the diameter of the bone not only along the scan path but also along the beam path (ie, from radiation source to detector). As I implied

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