September 1988, Vol 142, No. 9 >

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Article | September 1988

Bone Mineral Content in Infants: Which Machine or Which Bone? FREE

F. MIMOUNI, MD; R. C. TSANG, MB BS

Am J Dis Child. 1988;142(9):919. doi:10.1001/archpedi.1988.02150090017011.

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ABSTRACT

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Sir.—We read with interest the article by Vyhmeister et al,¹ who measured bone mineral content (BMC) at the radial and humeral sites using the Norland 278A (Norland Corp, Fort Atkinson, Wis) photon absorptiometer.

The statement in the abstract that "We tested... photon absorptiometric bone density measurements... The humerus was a more reliable site of measurement" is misleading. The sentence refers only to the machine the authors used, and not to photon absorptiometry. The study shows only that the Norland 278A is not a very sensitive instrument, and not that the humerus is a more reliable site. Using a larger bone (the humerus), the authors obtained a coefficient of variation (7% for instrument-reading error) larger than that obtained by Greer et al² (3.9%) on the smaller radius site using the Lunar instrument (Lunar Radiation Corp, Madison, Wis).

A potential danger of using an insensitive instrument to measure BMC

REFERENCES

ABSTRACT | REFERENCES

Vyhmeister NR, Linkhart TA, Hay S, et al: Measurement of bone mineral content in the term and preterm infant . AJDC 1987;;141:506-510.

Greer FR, Lane J, Weiner S, et al: An accurate and reproducible absorptiometric technique for determining bone mineral content in newborn infants . Pediatr Res 1983;;17:259-262.
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References

Vyhmeister NR, Linkhart TA, Hay S, et al: Measurement of bone mineral content in the term and preterm infant . AJDC 1987;;141:506-510.

Greer FR, Lane J, Weiner S, et al: An accurate and reproducible absorptiometric technique for determining bone mineral content in newborn infants . Pediatr Res 1983;;17:259-262.
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MIMOUNI FF, TSANG RC. Bone Mineral Content in Infants: Which Machine or Which Bone?. Am J Dis Child. 1988;142(9):919. doi:10.1001/archpedi.1988.02150090017011.

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