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January 1988, Vol 142, No. 1 >
Article | January 1988

Renal Transplantation in the Infant and Young Child FREE

Alok Kalia, MB, BS, MD; Ben H. Brouhard, MD; Luther B. Travis, MD; Robert R. M. Gifford, MD; Owen E. Winsett, MD
[+] Author Affiliations

Accepted for publication June 15, 1987.

Presented in part at the Annual Meeting of the Southern Society for Pediatric Research, New Orleans, Feb 7, 1986.

Reprint requests to the Division of Pediatric Nephrology and Diabetes, Child Health Center, Room 2-21, Route C-73, University of Texas Medical Branch, Galveston, TX 77550 (Dr Kalia).


Am J Dis Child. 1988;142(1):47-50. doi:10.1001/archpedi.1988.02150010057021.
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References
Comments

• Fourteen renal transplantations were performed in 13 children, aged 5 years or younger, including three infants. The mean duration of follow-up was 68 months, with a range of 14 to 203 months. Eleven children are alive; of these, nine had prolonged graft function. Graft survival rate was 92% at one year and 73% at two and five years following surgery. Sustained catch-up growth occurred in all growth-retarded children who underwent successful transplantation. At this writing, the oldest patient is 20 years of age and a junior in college; all school-age children are functioning at the appropriate grade level, except one, who is one year behind. The youngest child is 3 years old and is developing normally. Infants and young children appear to be good candidates for renal transplantation.

(AJDC 1988;142:47-50)

REFERENCES

1 +
Moel DI, Khalid MH, Butt MD:  Renal transplantation in children less than 2 years of age . J Pediatr 1981;;99:535-539.
2 +
Arbus GS, Hardy BE, Balfe JW, et al:  Cadaveric renal transplants in children under 6 years of age . Kidney Int 1983;;24:S111-S115.
3 +
Mahan JD, Mauer SM, Sibley RK, et al:  Congenital nephrotic syndrome: Evolution of medical management and results of renal transplantation . J Pediatr 1984;;105:549-557.
4 +
Hodson EM, Najarian JS, Kjellstrand CM, et al:  Renal transplantation in children ages 1 to 5 years . Pediatrics 1978;;61:458-464.
5 +
Miller LC, Bock GH, Lum CT, et al:  Transplantation of the adult kidney into the very small child: Long-term outcome . J Pediatr 1982;;100: 675-680.
6 +
Rizzoni G, Malekzadeh MH, Pennisi AJ, et al:  Renal transplantation in children less than 5 years of age . Arch Dis Child 1980;;55:532-536.
7 +
Ingelfinger JR, Grupe WE, Harmon WE, et al:  Growth acceleration following renal transplantation in children less than 7 years of age . Pediatrics 1981;;68:255-259.
8 +
Pennisi AJ, Costin G, Phillips LS, et al:  Linear growth in long-term renal allograft recipients . Clin Nephrol 1977;;8:415-421.
9 +
Bosque M, Munian A, Bewick M, et al:  Growth after renal transplants . Arch Dis Child 1983;;58:110-114.
10 +
Najarian JS, Simmons RL, Tallent MB, et al:  Renal transplantation in infants and children . Ann Surg 1971;;174:583-601.
11 +
McGraw ME, Haaka-Ikse K:  Neurologic-developmental sequelae of chronic renal failure in infancy . J Pediatr 1985;;106:579-583.
12 +
Geary DF, Fennell RS, Andriola M, et al:  Encephalopathy in children with chronic renal failure . J Pediatr 1980;;96:41-44.
13 +
Novello AC, Fine RN:  Renal transplantation in children: A review . Int J Pediatr Nephrol 1982;;3:87-98.
14 +
Cohen JJ, Harrington JT, Kassirer JP:  Pediatric renal transplantation . Kidney Int 1980;;18:519-529.
15 +
Hurley JK:  Kidney transplantation in infants . J Pediatr 1978;;93:538-539.
16 +
Fine RN:  Renal transplantation in children . J Pediatr 1982;;100:754-755.
17 +
Korsch BM, Fine RN:  The doctor's dilemma: Whether or not to recommend continuous renal dialysis or renal hemotransplantation for the child with end-stage renal disease . J Pediatr 1970;;77:505-507.
18 +
Cutler SJ, Ederer F:  Maximum utilization of the life table method in analyzing survival . J Chronic Dis 1958;;8:699-712.
19 +
Merrell M, Shulman LE:  Determination of prognosis in chronic disease, illustrated by systemic lupus erythematosus . J Chronic Dis 1955;;1: 12-32.
20 +
Tanner JM:  Physical growth and development , in Forfag J, Arneil GC (eds): Textbook of Pediatrics . New York, Churchill Livingstone Inc, 1973;, pp 224-291.
21 +
Smith DW: Growth and Its Disorders . Philadelphia, WB Saunders Co, 1977;, pp 58-59.
22 +
Kwun YA, Butt KMH, Kim KH, et al:  Successful renal transplantation in a 3-month-old infant . J Pediatr 1978;;92:426-429.
23 +
Iitaka K, Martin LW, Cox JA, et al:  Transplantation of cadaver kidneys from anencephalic donors . J Pediatr 1978;;93:216-220.
24 +
LaPlante MP, Kaufman JJ, Goldman R, et al:  Kidney transplantation in children . Pediatrics 1970;;46:665-677.
25 +
Warren S, Conley SB:  Nutritional considerations in infants on continuous peritoneal dialysis . Dialysis Transplant 1983;;12:263-266.
26 +
Gemma SL, Kalia A: Nutritional management of infants on continuous peritoneal dialysis. J Pediatr Perinatal Nutr, in press.
27 +
Kalia A, Travis LB, Brouhard B, et al:  Renal transplantation in children: A 17 year perspective , abstracted. Clin Res 1986;;34:264.
28 +
Fennell RS, Love JT, Carter RL, et al:  Statistical analysis of statural growth following kidney transplantation . Eur J Pediatr 1986;;145: 86-89.
29 +
Potter DE, Greifer I:  Statural growth of children with renal disease . Kidney Int 1978;;14: 334-339.
30 +
Travis LB, Chesney R, McEnery P, et al:  Growth and glucocorticoids in children with kidney disease . Kidney Int 1978;;14:365-368.
31 +
Reimold EW:  Intermittent prednisone therapy in children and adolescents after renal transplantation . Pediatrics 1973;;52:235-240.
32 +
Hoda Q, Hasinoff DJ, Arbus GS:  Growth following renal transplantation in children and adolescents . Clin Nephrol 1975;;3:6-9.
33 +
DeShazo CV, Simmons RL, Bernstein DM, et al:  Results of renal transplantation in 100 children . Surgery 1974;;76:461-468.
34 +
Lilly JR, Giles G, Hurwitz R, et al:  Renal transplantation in pediatric patients . Pediatrics 1971;;47:548-557.

Figures

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Moel DI, Khalid MH, Butt MD:  Renal transplantation in children less than 2 years of age . J Pediatr 1981;;99:535-539.
2 +
Arbus GS, Hardy BE, Balfe JW, et al:  Cadaveric renal transplants in children under 6 years of age . Kidney Int 1983;;24:S111-S115.
3 +
Mahan JD, Mauer SM, Sibley RK, et al:  Congenital nephrotic syndrome: Evolution of medical management and results of renal transplantation . J Pediatr 1984;;105:549-557.
4 +
Hodson EM, Najarian JS, Kjellstrand CM, et al:  Renal transplantation in children ages 1 to 5 years . Pediatrics 1978;;61:458-464.
5 +
Miller LC, Bock GH, Lum CT, et al:  Transplantation of the adult kidney into the very small child: Long-term outcome . J Pediatr 1982;;100: 675-680.
6 +
Rizzoni G, Malekzadeh MH, Pennisi AJ, et al:  Renal transplantation in children less than 5 years of age . Arch Dis Child 1980;;55:532-536.
7 +
Ingelfinger JR, Grupe WE, Harmon WE, et al:  Growth acceleration following renal transplantation in children less than 7 years of age . Pediatrics 1981;;68:255-259.
8 +
Pennisi AJ, Costin G, Phillips LS, et al:  Linear growth in long-term renal allograft recipients . Clin Nephrol 1977;;8:415-421.
9 +
Bosque M, Munian A, Bewick M, et al:  Growth after renal transplants . Arch Dis Child 1983;;58:110-114.
10 +
Najarian JS, Simmons RL, Tallent MB, et al:  Renal transplantation in infants and children . Ann Surg 1971;;174:583-601.
11 +
McGraw ME, Haaka-Ikse K:  Neurologic-developmental sequelae of chronic renal failure in infancy . J Pediatr 1985;;106:579-583.
12 +
Geary DF, Fennell RS, Andriola M, et al:  Encephalopathy in children with chronic renal failure . J Pediatr 1980;;96:41-44.
13 +
Novello AC, Fine RN:  Renal transplantation in children: A review . Int J Pediatr Nephrol 1982;;3:87-98.
14 +
Cohen JJ, Harrington JT, Kassirer JP:  Pediatric renal transplantation . Kidney Int 1980;;18:519-529.
15 +
Hurley JK:  Kidney transplantation in infants . J Pediatr 1978;;93:538-539.
16 +
Fine RN:  Renal transplantation in children . J Pediatr 1982;;100:754-755.
17 +
Korsch BM, Fine RN:  The doctor's dilemma: Whether or not to recommend continuous renal dialysis or renal hemotransplantation for the child with end-stage renal disease . J Pediatr 1970;;77:505-507.
18 +
Cutler SJ, Ederer F:  Maximum utilization of the life table method in analyzing survival . J Chronic Dis 1958;;8:699-712.
19 +
Merrell M, Shulman LE:  Determination of prognosis in chronic disease, illustrated by systemic lupus erythematosus . J Chronic Dis 1955;;1: 12-32.
20 +
Tanner JM:  Physical growth and development , in Forfag J, Arneil GC (eds): Textbook of Pediatrics . New York, Churchill Livingstone Inc, 1973;, pp 224-291.
21 +
Smith DW: Growth and Its Disorders . Philadelphia, WB Saunders Co, 1977;, pp 58-59.
22 +
Kwun YA, Butt KMH, Kim KH, et al:  Successful renal transplantation in a 3-month-old infant . J Pediatr 1978;;92:426-429.
23 +
Iitaka K, Martin LW, Cox JA, et al:  Transplantation of cadaver kidneys from anencephalic donors . J Pediatr 1978;;93:216-220.
24 +
LaPlante MP, Kaufman JJ, Goldman R, et al:  Kidney transplantation in children . Pediatrics 1970;;46:665-677.
25 +
Warren S, Conley SB:  Nutritional considerations in infants on continuous peritoneal dialysis . Dialysis Transplant 1983;;12:263-266.
26 +
Gemma SL, Kalia A: Nutritional management of infants on continuous peritoneal dialysis. J Pediatr Perinatal Nutr, in press.
27 +
Kalia A, Travis LB, Brouhard B, et al:  Renal transplantation in children: A 17 year perspective , abstracted. Clin Res 1986;;34:264.
28 +
Fennell RS, Love JT, Carter RL, et al:  Statistical analysis of statural growth following kidney transplantation . Eur J Pediatr 1986;;145: 86-89.
29 +
Potter DE, Greifer I:  Statural growth of children with renal disease . Kidney Int 1978;;14: 334-339.
30 +
Travis LB, Chesney R, McEnery P, et al:  Growth and glucocorticoids in children with kidney disease . Kidney Int 1978;;14:365-368.
31 +
Reimold EW:  Intermittent prednisone therapy in children and adolescents after renal transplantation . Pediatrics 1973;;52:235-240.
32 +
Hoda Q, Hasinoff DJ, Arbus GS:  Growth following renal transplantation in children and adolescents . Clin Nephrol 1975;;3:6-9.
33 +
DeShazo CV, Simmons RL, Bernstein DM, et al:  Results of renal transplantation in 100 children . Surgery 1974;;76:461-468.
34 +
Lilly JR, Giles G, Hurwitz R, et al:  Renal transplantation in pediatric patients . Pediatrics 1971;;47:548-557.

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