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Home Oxygen Promotes Weight Gain in Infants With Bronchopulmonary Dysplasia FREE

Jessie R. Groothuis, MD; Adam A. Rosenberg, MD
[+] Author Affiliations

Accepted for publication March 6, 1987.

Read in part before the Society for Pediatric Research, Washington, DC, May 5,1986, and the Ambulatory Pediatric Association, Washington, DC, May 8, 1986.

Reprint requests to Department of Pediatrics, University of Colorado School of Medicine, 4200 E Ninth Ave, Box C-230, Denver, CO 80262 (Dr Groothuis).


Am J Dis Child. 1987;141(9):992-995. doi:10.1001/archpedi.1987.04460090069028.
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• To study the effect of oxygen therapy on weight gain in bronchopulmonary dysplasia (BPD), the growth of 22 infants with BPD enrolled in a premature follow-up clinic and home oxygen program was examined retrospectively. Mean gestational age was 28 weeks (range, 26 to 33 weeks) and mean birth weight was 1110 g (range, 680 to 2000 g). After discharge, infants were monitored monthly to maintain transcutaneous oxygen tension over 55 mm Hg and/or pulse oximeter oxygen saturation over 92%. With appropriate home oxygen, all 22 infants grew as well as healthy, full-term infants (mean, 40th percentile; range, tenth to 80th percentile) when ages were corrected for prematurity. Parents discontinued oxygen therapy inappropriately in seven infants, and all seven experienced significant deceleration in weight gain. When home oxygen therapy was resumed, their weight gain improved, but the infants never regained their original percentiles during the study period. The 15 infants who continued home oxygen therapy maintained their original weight percentiles throughout the study period. These data support an important role for home nasal cannula oxygen in promoting weight gain in selected infants with BPD.

(AJDC 1987;141:992-995)

REFERENCES

Bancalari E, Gerhardt T:  Bronchopulmonary dysplasia . Pediatr Clin North Am 1986;;33: 1-23.
Koops BL, Abman SH, Accurso FJ:  Outpatient management and follow-up of bronchopulmonary dysplasia . Clin Perinatol 1984;;11:101-122.
Markestad T, Fitzhardinge PM:  Growth and development in children recovering from bronchopulmonary dysplasia . J Pediatr 1981;;98: 597-602.
Sauve RS, Singhal N:  Long-term morbidity of infants with bronchopulmonary dysplasia . Pediatrics 1985;;76:725-733.
Fitzhardinge PM:  Early growth and development in low birthweight infants following treatment in an intensive care nursery . Pediatrics 1975;;56:162-172.
Weinstein MR, Oh W:  Oxygen consumption in infants with bronchopulmonary dysplasia . J Pediatr 1981;;99:958-961.
Link to Article
Abman SH, Accurso FJ, Koops BL:  Experience with home oxygen in the management of infants with bronchopulmonary dysplasia . Clin Pediatr 1984;;23:471-476.
Link to Article
Pinney MA, Cotton EK:  Home management of bronchopulmonary dysplasia . Pediatrics 1976;; 58:856-859.
Campbell AN, Zarfin Y, Groenveld M:  Low flow oxygen therapy in infants . Arch Dis Child 1983;;58:795-798.
Link to Article
Donn S:  Cost effectiveness of home management of BPD . Pediatrics 1982;;70:320-321.
Fan LL, Voyles JB:  Determination of inspired oxygen delivered by nasal cannula in infants with chronic lung disease . J Pediatr 1982;;103:923-924.
Wallenstein S, Zucker CL, Fleiss JL:  Some statistical methods useful in circulation research . Circ Res 1980;;47:1-9.
Link to Article
Vohr BR, Bell EF, Oh W:  Infants with bronchopulmonary dysplasia: Growth pattern and neurodevelopmental outcome . AJDC 1982;; 136:443-447.
Meisels SJ, Plunkett JW, Roloff DW:  Growth and development of preterm infants with respiratory distress syndrome and bronchopulmonary dysplasia . Pediatrics 1986;;77:345-352.
Yu VY, Orgill AA, Lim SB, et al:  Growth and development of very low birthweight infants recovering from bronchopulmonary dysplasia . Arch Dis Child 1983;;58:791-794.
Link to Article
O'Brodovich HM, Mellins RB:  Bronchopulmonary dysplasia: Unresolved neonatal acute lung injury . Am Rev Respir Dis 1985;;132: 694-709.
Kurzner SI, Garg M, Bautista DB, et al:  Growth failure in infants with bronchopulmonary dysplasia is not due to malabsorption or poor intake , abstracted. Clin Res 1987;;35:229A.
Kurzner SI, Garg M, Bautista DB, et al:  Elevated metabolic rates correlated with growth failure in infants with bronchopulmonary dysplasia , abstracted. Clin Res 1987;;35:235A.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

Bancalari E, Gerhardt T:  Bronchopulmonary dysplasia . Pediatr Clin North Am 1986;;33: 1-23.
Koops BL, Abman SH, Accurso FJ:  Outpatient management and follow-up of bronchopulmonary dysplasia . Clin Perinatol 1984;;11:101-122.
Markestad T, Fitzhardinge PM:  Growth and development in children recovering from bronchopulmonary dysplasia . J Pediatr 1981;;98: 597-602.
Sauve RS, Singhal N:  Long-term morbidity of infants with bronchopulmonary dysplasia . Pediatrics 1985;;76:725-733.
Fitzhardinge PM:  Early growth and development in low birthweight infants following treatment in an intensive care nursery . Pediatrics 1975;;56:162-172.
Weinstein MR, Oh W:  Oxygen consumption in infants with bronchopulmonary dysplasia . J Pediatr 1981;;99:958-961.
Link to Article
Abman SH, Accurso FJ, Koops BL:  Experience with home oxygen in the management of infants with bronchopulmonary dysplasia . Clin Pediatr 1984;;23:471-476.
Link to Article
Pinney MA, Cotton EK:  Home management of bronchopulmonary dysplasia . Pediatrics 1976;; 58:856-859.
Campbell AN, Zarfin Y, Groenveld M:  Low flow oxygen therapy in infants . Arch Dis Child 1983;;58:795-798.
Link to Article
Donn S:  Cost effectiveness of home management of BPD . Pediatrics 1982;;70:320-321.
Fan LL, Voyles JB:  Determination of inspired oxygen delivered by nasal cannula in infants with chronic lung disease . J Pediatr 1982;;103:923-924.
Wallenstein S, Zucker CL, Fleiss JL:  Some statistical methods useful in circulation research . Circ Res 1980;;47:1-9.
Link to Article
Vohr BR, Bell EF, Oh W:  Infants with bronchopulmonary dysplasia: Growth pattern and neurodevelopmental outcome . AJDC 1982;; 136:443-447.
Meisels SJ, Plunkett JW, Roloff DW:  Growth and development of preterm infants with respiratory distress syndrome and bronchopulmonary dysplasia . Pediatrics 1986;;77:345-352.
Yu VY, Orgill AA, Lim SB, et al:  Growth and development of very low birthweight infants recovering from bronchopulmonary dysplasia . Arch Dis Child 1983;;58:791-794.
Link to Article
O'Brodovich HM, Mellins RB:  Bronchopulmonary dysplasia: Unresolved neonatal acute lung injury . Am Rev Respir Dis 1985;;132: 694-709.
Kurzner SI, Garg M, Bautista DB, et al:  Growth failure in infants with bronchopulmonary dysplasia is not due to malabsorption or poor intake , abstracted. Clin Res 1987;;35:229A.
Kurzner SI, Garg M, Bautista DB, et al:  Elevated metabolic rates correlated with growth failure in infants with bronchopulmonary dysplasia , abstracted. Clin Res 1987;;35:235A.

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