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Nonimmune Hydrops Fetalis in Noonan's Syndrome

Anne Marie Oudesluys-Murphy, MB
Am J Dis Child. 1987;141(5):478-479. doi:10.1001/archpedi.1987.04460050020016.
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Sir.—In reference to Bawle and Black's1 article on nonimmune hydrops fetalis in Noonan's syndrome, I wish to report a similar case.

Patient Report.—This boy was the first child of healthy, nonrelated Dutch parents. The pregnancy progressed normally until the membranes ruptured prematurely at 35 weeks' gestation. A cesarean section was performed because of signs of fetal distress and breech presentation. At birth he weighed 1920 g, was 41 cm long, and had an occipitofrontal circumference of 33 cm. He had generalized edema and a strange appearance, with low-set ears, micrognathia, and a low hairline. The thorax was broad and barrel shaped. Initially there was slight respiratory distress, but a chest roentgenogram revealed no abnormalities, and no cardiac murmurs were heard. The liver was palpable 2 cm below the right costal margin.

The blood group of the infant was B Rh-Positive, and that of the mother A Rh-positive.


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