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Antibody Response to Measles Vaccine With DTPP

T. Jacob John, FRCP(E), PhD; Eric A. F. Simoes, MD, DCH; R. Selvakumar, MVSc; Vinohar Balrai, MD
Am J Dis Child. 1987;141(1):14. doi:10.1001/archpedi.1987.04460010014010.
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Sir.—We previously reported1 the advantages of giving measles vaccine mixed with diphtheria and tetanus toxoids and pertussis (DTP) vaccine or diphtheria, tetanus, pertussis, poliomyelitis (DTPP) vaccine with one syringe and needle. We found that measles virus survived mixing with these vaccines and remained potentially immunogenic for at least four hours. Herein, we report the antibody response of monkeys and children to measles vaccine mixed with DTPP vac

Antibody Response of Monkeys and Children Inoculated With Measles Vaccine Alone or Mixed With DTPP Vaccine*

Subjects Vaccine Route n No. Seroconverted (Antibody Titer ≥8) GMT Monkeys Monkeys Monkeys Monkeys Children Children Measles Measles Measles and DTPP Measles and DTPP Measles Measles and DTPP SC IM SC IM IM IM 10 10 10 10 10 10 9 9 9 9 10 10 37 47 64 47 34 37

*DTPP indicates diphtheria, tetanus, pertussis, poliomyelitis; GMT, geometric mean titer of antibody; SC, subcutaneous;

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