In Reply.—Dr Amir and colleagues have offered data collaborating our assertion that UTI is a common cause of fever in young infants. They also confirm the observation that UTI is more common in male than in female infants.
In our prospective study of fever in infants under 3 months of age, we found UTI to be more common in the uncircumcised (12 patients) than in the circumcised (two patients) infants. The preponderence of infections in uncircumcised infants was unexpected, since overall during the same period, 75% of the male infants born in our institution were circumcised. Wiswell et al retrospectively reviewed the medical records of all infants born in their institution who subsequently were admitted to their hospital with UTI in the first year of life. They reported UTIs in four (0.2%) of 1919 circumcised male infants and in 24 (4.1%) of 583 uncircumcised male infants (4.1%).