Sweet's Syndrome With Multifocal Sterile Osteomyelitis FREE

Thomas C. Edwards, MD; F. Bruder Stapleton, MD; Michael J. Bond, MD; Fred F. Barrett, MD

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Accepted for publication May 8, 1986.

Reprint requests to Pediatric Research Laboratory, 956 Court Ave, Room B310, Memphis, TN 38163 (Dr Stapleton).

Am J Dis Child. 1986;140(8):817-818. doi:10.1001/archpedi.1986.02140220099042.

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ABSTRACT

ABSTRACT | REFERENCES

• Sweet's syndrome is a rare condition characterized by fever, leukocytosis, dense dermal infiltration of leukocytes, and painful indurated cutaneous plaques. We describe a 23-month-old male infant with the typical cutaneous manifestations of Sweet's syndrome and painful extremities that limited ambulation. Evaluation revealed multifocal sterile osteomyelitis of both tibia. After the institution of systemic corticosteroid therapy, the patient's symptoms resolved, and bone scans normalized. After one year of follow-up, the patient has intermittent recrudescences that resolve during corticosteroid therapy. Sterile multifocal osteomyelitis represents another clinical manifestation of Sweet's syndrome.

(AJDC 1986;140:817-818)

REFERENCES

ABSTRACT | REFERENCES

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Levin DL, Esterly NB, Herman JJ, et al: The Sweet syndrome in children . J Pediatr 1981;; 99:73-78.

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Leibowitz MR, Rippey JJ, Bezwoda WR, et al: Unusual aspects of febrile neutrophilic dermatosis (Sweet's syndrome) . S Afr Med J 1982;;62:375-378.

Cooper PH, Innes DJ, Greer KE: Acute febrile neutrophilic dermatosis (Sweet's syndrome) and myeloproliferative disorders . Cancer 1983;;51:1518-1526.

Su D, Liu HN: Diagnostic criteria for Sweet's syndrome . Cutis 1986;;37:167-172.

Bjorksten B, Gustavson KH, Eriksson B, et al: Chronic recurrent multifocal symmetrical osteomyelitis and pustulosis palmo-plantaris . J Pediatr 1978;;93:227-231.

Meller Y, Yagupsky P, Elitsur Y, et al: Chronic multifocal symmetrical osteomyelitis: Report of two cases in bedouin infants . AJDC 1984;;138:349-351.

Paller AS, Pachman L, Rich K, et al: Pustulosis palmaris et plantaris: Its association with chronic recurrent multifocal osteomyelitis . J Am Acad Dermatol 1985;;12:927-930.

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