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Periorbital Cellulitis Complicating Adenovirus Infection

JOSEPH HERMAN, MD; ELIAHU KATZUNI, MD
Am J Dis Child. 1986;140(8):745. doi:10.1001/archpedi.1986.02140220027023.
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Sir.—Periorbital (preseptal) cellulitis is a soft-tissue infection often associated with a history of antecedent coryza, trauma, or local skin inflammation.1 Recent reports emphasize management rather than pathogenesis. The role of sinusitis as a predisposing factor has been controversial, with some authors regarding it as a complication of the process that initiates the cellulitis2,3 and others implying a direct causation.1,4 The most frequently encountered pathogens have been Haemophilus influenzae in those patients with an upper respiratory tract infection; staphylococci and streptococci are etiologic with adjacent trauma or skin inflammation.2 The question of whether or not viruses can predispose to periorbital cellulitis has been raised5 but, with the exception of Herpesvirus varicellae mentioned in connection with eyelid infection,3,4 not one known to produce rhinitis has been identified. We encountered a 13-month-old child with pharyngoconjunctival fever caused by type 7a adenovirus in whom cellulitis developed in

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