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Prognosis of Herpes Zoster in Healthy Children FREE

Carol L. Wurzel, MD; Joel Kahan, MD; Michael Heitler, MD; Lorry G. Rubin, MD
[+] Author Affiliations

Accepted for publication Jan 28, 1986.

Reprint requests to Schneider Children's Hospital, Long Island Jewish Medical Center, New Hyde Park, NY 11042 (Dr Wurzel).


Am J Dis Child. 1986;140(5):477-478. doi:10.1001/archpedi.1986.02140190087033.
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• Previous investigators have suggested that herpes zoster may be the presenting sign of a malignancy. However, no data have been available concerning the prognosis of herpes zoster in normal children. To assess outcome and prognosis for healthy children with a diagnosis of herpes zoster, we collected and reviewed 22 cases of herpes zoster from 90 pediatric practices in our community. In all cases, the illness was of short duration and resolved completely. Patients were followed up by their pediatricians for a mean of 4.2 years, and in no case did malignancy manifest subsequent to the zoster infection. We conclude that herpes zoster is a relatively benign infection in children and, given the period of follow-up, the onset of zoster does not appear to herald the occurrence of malignancy in this population.

(AJDC 1986;140:477-478)

REFERENCES

Ray CG:  Chickenpox (varicella) and herpes zoster , in Petersdorf RG, Adams RD, Braunwald E, et al (eds): Harrison's Principles of Internal Medicine . New York, McGraw-Hill International Book Inc, 1983;, pp 1121-1125.
Miller LH, Brunell PA:  Zoster, reinfection or activation of latent virus? Am J Med 1970;;49: 480-483.
Feldman S, Hughes WT, Kim HY:  Herpes zoster in children with cancer . AJDC 1973;;126: 178-183.
Hartley WJ, Mandal BK:  Herpes zoster in childhood . Practitioner 1982;;226:766-770.
Muller SA:  Association of zoster and malignant disorders in children . Arch Dermatol 1967;; 96:657-664.
Bacon GE, Oliver WJ, Shapiro BA:  Factors contributing to severity of herpes zoster in children . J Pediatr 1965;;67:768-771.
Ragozzino MW, Melton LJ, Kurland LT, et al:  Risk of cancer after herpes zoster . N Engl J Med 1982;;307:393-397.
Guess HA, Broughton DD, Melton LJ, et al:  Epidemiology of herpes zoster in children and adolescents . Pediatrics 1985;;76:512-517.
Brunell PA, Miller LH, Lovejoy F:  Zoster in children . AJDC 1968;;115:432-437.
Latif R, Shope TC:  Herpes zoster in normal and immunocompromised children . AJDC 1983;;137:801-802.
Rogers RS, Tindall JP:  Herpes zoster in children . Arch Dermatol 1972;;106:204-207.
Winkelmann RK, Perry HO:  Herpes zoster in children . JAMA 1959;;171:876-880.
Saracli T, Scott RB:  Herpes zoster in children . Med Ann DC 1970;;39:195-197.
Hope-Simpson RE:  The nature of herpes zoster: A long-term study and a new hypothesis . Proc R Soc Med 1965;;58:9-20.
Preblud SR:  Age specific risks of varicella complications . Pediatrics 1981;;68:14-17.
Gordon JE:  Chickenpox: An epidemiological review . Am J Med Sci 1962;;244:363-389.
Ross AH:  Modification of chicken pox in family contacts by administration of γ globulin . N Engl J Med 1962;;267:369-376.
Wehrle PF:  Bilateral herpes zoster in a child following exposure to chicken pox . JAMA 1976;;235:2238.
Wyburn-Mason R:  Malignant change arising in tissues affected by herpes . Br Med J 1955;;2:1106-1109.

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References

Ray CG:  Chickenpox (varicella) and herpes zoster , in Petersdorf RG, Adams RD, Braunwald E, et al (eds): Harrison's Principles of Internal Medicine . New York, McGraw-Hill International Book Inc, 1983;, pp 1121-1125.
Miller LH, Brunell PA:  Zoster, reinfection or activation of latent virus? Am J Med 1970;;49: 480-483.
Feldman S, Hughes WT, Kim HY:  Herpes zoster in children with cancer . AJDC 1973;;126: 178-183.
Hartley WJ, Mandal BK:  Herpes zoster in childhood . Practitioner 1982;;226:766-770.
Muller SA:  Association of zoster and malignant disorders in children . Arch Dermatol 1967;; 96:657-664.
Bacon GE, Oliver WJ, Shapiro BA:  Factors contributing to severity of herpes zoster in children . J Pediatr 1965;;67:768-771.
Ragozzino MW, Melton LJ, Kurland LT, et al:  Risk of cancer after herpes zoster . N Engl J Med 1982;;307:393-397.
Guess HA, Broughton DD, Melton LJ, et al:  Epidemiology of herpes zoster in children and adolescents . Pediatrics 1985;;76:512-517.
Brunell PA, Miller LH, Lovejoy F:  Zoster in children . AJDC 1968;;115:432-437.
Latif R, Shope TC:  Herpes zoster in normal and immunocompromised children . AJDC 1983;;137:801-802.
Rogers RS, Tindall JP:  Herpes zoster in children . Arch Dermatol 1972;;106:204-207.
Winkelmann RK, Perry HO:  Herpes zoster in children . JAMA 1959;;171:876-880.
Saracli T, Scott RB:  Herpes zoster in children . Med Ann DC 1970;;39:195-197.
Hope-Simpson RE:  The nature of herpes zoster: A long-term study and a new hypothesis . Proc R Soc Med 1965;;58:9-20.
Preblud SR:  Age specific risks of varicella complications . Pediatrics 1981;;68:14-17.
Gordon JE:  Chickenpox: An epidemiological review . Am J Med Sci 1962;;244:363-389.
Ross AH:  Modification of chicken pox in family contacts by administration of γ globulin . N Engl J Med 1962;;267:369-376.
Wehrle PF:  Bilateral herpes zoster in a child following exposure to chicken pox . JAMA 1976;;235:2238.
Wyburn-Mason R:  Malignant change arising in tissues affected by herpes . Br Med J 1955;;2:1106-1109.

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