We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Therapeutic Uses of Calcium Channel-Blocking Drugs in the Young

Cornelia Cho, MD; Albert W. Pruitt, MD; James J. Corrigan Jr, MD; Hugh D. Allen, MD; Richard Hong, MD; C. Thomas Kisker, MD
Am J Dis Child. 1986;140(4):360-366. doi:10.1001/archpedi.1986.02140180094034.
Text Size: A A A
Published online


Calcium channel—blocking drugs, also referred to as calcium antagonists and slow-channel blockers, have had a major impact on the treatment of cardiovascular disorders such as angina, arrhythmias, and hypertension in adults. Although the drugs are labeled for use in only a limited number of pathologic conditions in children, clinical evaluations in a variety of illnesses are under way. Among the exciting potential uses are the treatment of asthma, control of premature labor, and as adjunctive therapy in cancer chemotherapy. The purpose of this report is to review research that has relevance to the therapeutic application of calcium channel blockers in the young.

PHARMACOLOGY  Calcium and its regulation are vital to a wide range of physiologic functions, including myocardial contractility, nerve impulse transmission, smooth-muscle contraction, and secretory activity of exocrine glands. An essential role for calcium was suggested by Ringer1,2 in 1883, when he demonstrated that the addition of calcium


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.