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Intracranial Hemorrhage in Premature Infants FREE

WILLIAM C. HANIGAN, MD, PHD; WILLIAM F. POWERS, MD; GAIL KENNEDY, MD; FRANK ROEMISCH, MD
Am J Dis Child. 1986;140(3):184. doi:10.1001/archpedi.1986.02140170010001.
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Sir.—Meidell et al1 have shown that of 40 premature infants, representing all inborn patients admitted to their service over a 12-month period, 15 (38%) experienced an intracranial hemorrhage (ICH) at a mean time of 1.9 hours after birth. The SE of the mean was 0.2 hours, which suggests that the hemorrhages were clustered into a reasonably small range. While their data may be accurate, we feel that it may not be representative of other investigators' observations.

We have been conducting a study involving all admissions to our highrisk nursery over the past ten months.

In that period, 94 infants weighing less than 1,500 g were admitted and received sonograms within 12 hours. Five (5.3%) of the infants (three inborn) had sustained an ICH. Two previous studies2,3 demonstrated that only 5% to 10% of all admissions hemorrhaged within 12 hours. A fourth study,4 which entered alternate patients and included

REFERENCES

Meidell R, Marinelli P, Pettett G:  Perinatal factors associated with early-onset intracranial hemorrhage in premature infants: A prospective study . AJDC 1985;;139:160-163.
Dolfin T, Skidmore MB, Fong KW, et al:  Incidence, severity, and timing of subependymal and intraventricular hemorrhages in preterm infants born in a perinatal unit as detected by serial real-time ultrasound . Pediatrics 1983;;71: 541-546.
Levene MI, Wigglesworth JS, Dubowitz V:  Cerebral structure and intraventricular haemorrhage in the neonate: A real-time ultrasound study . Arch Dis Child 1981;;56:416-424.
Partridge JC, Babcock DS, Steichen JJ, et al:  Optimal timing for diagnostic cranial ultrasound in low-birth-weight infants: Detection of intracranial hemorrhage and ventricular dilation . J Pediatr 1983;;102:281-287.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Meidell R, Marinelli P, Pettett G:  Perinatal factors associated with early-onset intracranial hemorrhage in premature infants: A prospective study . AJDC 1985;;139:160-163.
Dolfin T, Skidmore MB, Fong KW, et al:  Incidence, severity, and timing of subependymal and intraventricular hemorrhages in preterm infants born in a perinatal unit as detected by serial real-time ultrasound . Pediatrics 1983;;71: 541-546.
Levene MI, Wigglesworth JS, Dubowitz V:  Cerebral structure and intraventricular haemorrhage in the neonate: A real-time ultrasound study . Arch Dis Child 1981;;56:416-424.
Partridge JC, Babcock DS, Steichen JJ, et al:  Optimal timing for diagnostic cranial ultrasound in low-birth-weight infants: Detection of intracranial hemorrhage and ventricular dilation . J Pediatr 1983;;102:281-287.

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