Article |

Persistent Secondary Hyperparathyroidism in Infants Fed Humanized Cow Milk Formula

Am J Dis Child. 1985;139(12):1182. doi:10.1001/archpedi.1985.02140140016012.
Text Size: A A A
Published online

Sir.—Would Venkataraman and colleagues1 discuss the long-term implications of persistent secondary hyperparathyroidism in infants fed humanized cow milk formula?

Their observation was prompted by the appearance of tetany in formulafed infants, but serum parathyroid hormone levels were also increased in formula-fed infants without symptoms. Tetany in infants fed older formulas is followed by enamel hypoplasia in deciduous teeth2; and even without tetany young children fed formula as infants have twice as much dental caries as their breast-fed counterparts.3

As Venkataraman et al1 observe, all bottle-feeds have excessive phosphorus and, to a lesser degree, excessive calcium compared with human milk. In the long run is this likely to produce more bone mineral, less bone mineral, or qualitatively different bone mineral? In at least two animal species high calcium intakes and increased mineral retention in early life produce less stable bone mineral and greater calcium loss during


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.