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Tissue pH Monitoring by a Disposable Sensor in Critically Ill Neonates FREE

Urmila Chaudhry, MD; Rama Bhat, MD
[+] Author Affiliations

Presented in part before the Second International Conference on Fetal and Neonatal Physiological Measurements, Oxford, England, April 2, 1984.

Reprint requests to Department of Pediatrics, University of Illinois Hospital, 840 S Wood St, Chicago, IL 60612 (Dr Bhat).


Am J Dis Child. 1985;139(10):1049-1053. doi:10.1001/archpedi.1985.02140120095036.
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• Using a new disposable polymer sensor, tissue pH was continuously monitored successfully in 33 critically ill neonates. Tissue pH correlated well with the arterial pH at wide pH ranges [n = 476; r=.84; y = 0.46 +(0.94)x] Tissue pH changes accurately reflected the arterial pH during both respiratory and metabolic acidosis and alkalosis. During severe metabolic acidosis (arterial pH <7.10) tissue pH was lower than arterial pH. No complications were encountered during or after monitoring. Compared with earlier studies using a glass electrode, this electrode reflects a marked technologic improvement because of its ease of application, longevity of use, disposability, and decreased risk of complications in small preterm infants. Unlike transcutaneous oxygen and carbon dioxide sensors, this device is invasive but is not heated and does not require frequent site changes.

(AJDC 1985;139:1049-1053)

REFERENCES

Philip AGS:  Noninvasive diagnostic techniques in newborn infants . Pediatr Clin North Am 1982;;29:1275-1298.
Weisman LE, Merenstein GB, Steenbarger JR:  The effect of lumbar puncture position in sick neonates . AJDC 1983;;137:1077-1079.
Couch NP, Dmochowski JR, Van De Water JM, et al:  Muscle surface pH as an index of peripheral perfusion in man . Ann Surg 1971;;173: 173-183.
Filler RM, Das JB, Espinosa HM:  Clinical experience with continuous muscle pH monitoring as an index of tissue perfusion and oxygenation and acid-base status . Surgery 1972;;72:23-33.
Filler RM, Das JB, Haase GM, et al:  Muscle surface pH as a monitor of tissue perfusion and acid-base status . J Pediatr Surg 1971;;6:535-542.
Bhat R, Vidyasagar D, Asonye UO, et al:  Continuous tissue pH monitoring in critically ill neonates . J Pediatr 1980;;97:445-450.
LeBlanc OH Jr, Brown JF Jr, Klebe JF, et al:  Polymer membrane sensors for continuous intravascular monitoring of blood pH . J Appl Physiol 1976;;40:644-647.
Lemieux MD, Smith RN, Couch NP, et al:  Surface pH and redox potential of skeletal muscle in graded hemorrhage . Surgery 1969;;65:457-561.
Hochberg HM, Lauersen NH, George MED, et al:  Evaluation of continuous monitoring of tissue pH in cats . Am J Obstet Gynecol 1978;; 131:770-774.
Das JB, Joshi ID, Philippart AI:  Continuous monitoring of pH in the tissue mode: Evaluation of a miniature sensor during acidosis and tissue hypoperfusion . J Pediatr Surg 1983;;18: 914-921.
Tremper KK, Waxman K, Shoemaker WC:  Effects of hypoxia and shock on transcutaneous Po2 values in dogs . Crit Care Med 1979;;71:526-531.

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References

Philip AGS:  Noninvasive diagnostic techniques in newborn infants . Pediatr Clin North Am 1982;;29:1275-1298.
Weisman LE, Merenstein GB, Steenbarger JR:  The effect of lumbar puncture position in sick neonates . AJDC 1983;;137:1077-1079.
Couch NP, Dmochowski JR, Van De Water JM, et al:  Muscle surface pH as an index of peripheral perfusion in man . Ann Surg 1971;;173: 173-183.
Filler RM, Das JB, Espinosa HM:  Clinical experience with continuous muscle pH monitoring as an index of tissue perfusion and oxygenation and acid-base status . Surgery 1972;;72:23-33.
Filler RM, Das JB, Haase GM, et al:  Muscle surface pH as a monitor of tissue perfusion and acid-base status . J Pediatr Surg 1971;;6:535-542.
Bhat R, Vidyasagar D, Asonye UO, et al:  Continuous tissue pH monitoring in critically ill neonates . J Pediatr 1980;;97:445-450.
LeBlanc OH Jr, Brown JF Jr, Klebe JF, et al:  Polymer membrane sensors for continuous intravascular monitoring of blood pH . J Appl Physiol 1976;;40:644-647.
Lemieux MD, Smith RN, Couch NP, et al:  Surface pH and redox potential of skeletal muscle in graded hemorrhage . Surgery 1969;;65:457-561.
Hochberg HM, Lauersen NH, George MED, et al:  Evaluation of continuous monitoring of tissue pH in cats . Am J Obstet Gynecol 1978;; 131:770-774.
Das JB, Joshi ID, Philippart AI:  Continuous monitoring of pH in the tissue mode: Evaluation of a miniature sensor during acidosis and tissue hypoperfusion . J Pediatr Surg 1983;;18: 914-921.
Tremper KK, Waxman K, Shoemaker WC:  Effects of hypoxia and shock on transcutaneous Po2 values in dogs . Crit Care Med 1979;;71:526-531.

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