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Type 2 Corticosterone Methyloxidase Defect in a 2-Year-Old Iranian Jewish Child

Am J Dis Child. 1984;138(12):1154. doi:10.1001/archpedi.1984.02140500058020.
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Sir.—The article "Selective Hypoaldosteronism in Infancy" by Curtis et al1 brought back to mind a patient who subsequently became one of the cases cited by Rosler et al2 in their review article on this subject.

Report of a Case.—A male infant was the product of a full-term, uncomplicated pregnancy of Iranian Jewish parents. Both parents were 26 years of age. There was consanguinity in the family; the maternal great-grandmother was the paternal grandmother's sister. A previous male sibling was normal and was 4 years old at the time of the infant's birth.

The infant was a poor feeder from birth with chronic constipation and was admitted to the University of California—San Diego Hospital at 3½ months of age for failure to thrive. The results of his physical examination were normal, except for weight below the third percentile. Laboratory findings, including complete blood cell count, ESR, blood


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