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Nodular Regenerative Hyperplasia of the Liver in a 4-Month-Old Infant FREE

Joan M. Mones, DO; Mario J. Saldana, MD
[+] Author Affiliations

Reprint requests to Department of Pathology (D-33), University of Miami School of Medicine, PO Box 016960, Miami, FL 33101 (Dr Mones).


Am J Dis Child. 1984;138(1):79-81. doi:10.1001/archpedi.1984.02140390067020.
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• Nodular regenerative hyperplasia of the liver is a rare condition that primarily affects adult patients. We report a case of this disease in a 4-month-old infant with coexisting globoid cell leukodystrophy (Krabbe's disease). Based on an analysis of this case and a review of the literature, we concluded that the two disorders were probably unrelated.

(AJDC 1984;138:79-81)

REFERENCES

Stromeyer FW, Ishak KG:  Nodular transformation (nodular 'regenerative' hyperplasia) of the liver . Hum Pathol 1981;;12:60-71.
Sogaard PE:  Nodular transformation of the liver, α-fetoprotein and hepatocellular carcinoma . Hum Pathol 1981;;12:1052.
Friede RL: Developmental Neuropathology . New York, Springer-Verlag, 1975;, pp 433-442.
Alperstein G, Kahn E, Aiges H, et al:  Nodular regenerative hyperplasia of the liver: An unusual cause of portal hypertension in childhood . Am J Dis Child 1981;;135:572-574.
Shorey J, Weinberg MN, Frenkel EP, et al:  Nodular regenerative hyperplasia of the liver in a case of myelofibrosis with extramedullary hematopoiesis and secondary portal venous hypertension . Am J Clin Pathol 1979;;72:122-125.
Wanless IR, Godwin TA, Allen F, et al:  Nodular regenerative hyperplasia of the liver in hematologic disorders: A possible response to obliterative portal venopathy . Medicine 1980;;59: 367-379.
Miyai K, Bonin ML:  Nodular regenerative hyperplasia of the liver . Am J Clin Pathol 1980;; 73:267-271.
Wanless IR, Solt C, Kortan P, et al:  Nodular regenerative hyperplasia of the liver associated with macroglobulinemia . Am J Med 1981;;70: 1203-1209.
Smith JC:  Noncirrhotic nodulation of the liver . Arch Pathol Lab Med 1978;;102:398-401.
Steiner PE:  Nodular regenerative hyperplasia of the liver . Am J Pathol 1959;;35:943-953.
Knowles DM, Kaye GI, Godman GC:  Nodular regenerative hyperplasia of the liver . Gastroenterology 1975;;69:746-751.
Thung SN, Gerber MA, Bodenheimer HC:  Nodular regenerative hyperplasia of the liver in a patient with diabetes mellitus . Cancer 1982;;49: 543-546.
Reisman T, Levi JU, Zeppa R, et al:  Noncirrhotic portal hypertension in Felty's syndrome . Dig Dis Sci 1977;;22:145-148.
Blendis LM, Parkinson MC, Shilkin KB, et al:  Nodular regenerative hyperplasia of the liver in Felty's syndrome . Q J Med 1974;;43:25-32.
Harris M, Rash RM, Dymock IW:  Nodular, noncirrhotic liver associated with portal hypertension in a patient with rheumatoid arthritis . J Clin Pathol 1974;;27:963-966.
Qizilbash AH, Castelli M:  Nodular regenerative hyperplasia of the liver: Diagnosis by liver biopsy . Can Med Assoc J 1980;;122:1151-1154.
Ranstrom S:  Miliary hepatocellular adenomatosis . Acta Pathol Microbiol Scand 1953;;33: 225-229.
Lurie B, Novis B, Bank S, et al:  CRST syndrome and nodular transformation of the liver . Gastroenterology 1973;;64:457-461.
Bredfeldt JE, Havey AL:  Nodular regenerative hyperplasia of the liver following renal transplantation . Dig Dis Sci 1981;;26:271-274.
Connolly CE, O'Brien MJ:  Nodular transformation of the liver: Report of a case . Hum Pathol 1977;;8:350-352.
Rossi L, Ravera M, Repetti G, et al:  Longterm administration of DDT or phenobarbital-Na in Wistar rats . Int J Cancer 1977;;19:179-185.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

Stromeyer FW, Ishak KG:  Nodular transformation (nodular 'regenerative' hyperplasia) of the liver . Hum Pathol 1981;;12:60-71.
Sogaard PE:  Nodular transformation of the liver, α-fetoprotein and hepatocellular carcinoma . Hum Pathol 1981;;12:1052.
Friede RL: Developmental Neuropathology . New York, Springer-Verlag, 1975;, pp 433-442.
Alperstein G, Kahn E, Aiges H, et al:  Nodular regenerative hyperplasia of the liver: An unusual cause of portal hypertension in childhood . Am J Dis Child 1981;;135:572-574.
Shorey J, Weinberg MN, Frenkel EP, et al:  Nodular regenerative hyperplasia of the liver in a case of myelofibrosis with extramedullary hematopoiesis and secondary portal venous hypertension . Am J Clin Pathol 1979;;72:122-125.
Wanless IR, Godwin TA, Allen F, et al:  Nodular regenerative hyperplasia of the liver in hematologic disorders: A possible response to obliterative portal venopathy . Medicine 1980;;59: 367-379.
Miyai K, Bonin ML:  Nodular regenerative hyperplasia of the liver . Am J Clin Pathol 1980;; 73:267-271.
Wanless IR, Solt C, Kortan P, et al:  Nodular regenerative hyperplasia of the liver associated with macroglobulinemia . Am J Med 1981;;70: 1203-1209.
Smith JC:  Noncirrhotic nodulation of the liver . Arch Pathol Lab Med 1978;;102:398-401.
Steiner PE:  Nodular regenerative hyperplasia of the liver . Am J Pathol 1959;;35:943-953.
Knowles DM, Kaye GI, Godman GC:  Nodular regenerative hyperplasia of the liver . Gastroenterology 1975;;69:746-751.
Thung SN, Gerber MA, Bodenheimer HC:  Nodular regenerative hyperplasia of the liver in a patient with diabetes mellitus . Cancer 1982;;49: 543-546.
Reisman T, Levi JU, Zeppa R, et al:  Noncirrhotic portal hypertension in Felty's syndrome . Dig Dis Sci 1977;;22:145-148.
Blendis LM, Parkinson MC, Shilkin KB, et al:  Nodular regenerative hyperplasia of the liver in Felty's syndrome . Q J Med 1974;;43:25-32.
Harris M, Rash RM, Dymock IW:  Nodular, noncirrhotic liver associated with portal hypertension in a patient with rheumatoid arthritis . J Clin Pathol 1974;;27:963-966.
Qizilbash AH, Castelli M:  Nodular regenerative hyperplasia of the liver: Diagnosis by liver biopsy . Can Med Assoc J 1980;;122:1151-1154.
Ranstrom S:  Miliary hepatocellular adenomatosis . Acta Pathol Microbiol Scand 1953;;33: 225-229.
Lurie B, Novis B, Bank S, et al:  CRST syndrome and nodular transformation of the liver . Gastroenterology 1973;;64:457-461.
Bredfeldt JE, Havey AL:  Nodular regenerative hyperplasia of the liver following renal transplantation . Dig Dis Sci 1981;;26:271-274.
Connolly CE, O'Brien MJ:  Nodular transformation of the liver: Report of a case . Hum Pathol 1977;;8:350-352.
Rossi L, Ravera M, Repetti G, et al:  Longterm administration of DDT or phenobarbital-Na in Wistar rats . Int J Cancer 1977;;19:179-185.

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